College of American Pathologists

  Cytogenetics Topic Center

  Updated February 17, 2014


Articles Articles

Saxe DF, Persons DL, Wolff DJ, Theil KS “Validation of Fluorescence In Situ Hybridization Using an Analyte-Specific Reagent for Detection of Abnormalities Involving the Mixed Lineage Leukemia Gene” Arch Pathol Lab Med 2012; 136(1): 47-52.

Brothman, Arthur R.; Dolan, Michelle M.; Goodman, Barbara K.; Park, Jonathan P.; Persons, Diane L.; Saxe, Debra F.; Tepperberg, James H.; Tsuchiya, Karen D.; Van Dyke, Daniel L.; Wilson, Kathleen S.; Wolff, Daynna J.; Theil, Karl S.
College of American Pathologists/American College of Medical Genetics proficiency testing for constitutional cytogenomic microarray analysisGenet Med 2011;13(9): 765-769.

Wolff DJ, Bagg A, Cooley LD, Dewald GW, Hirsch BA, Jacky PB, Rao KW, Rao PN. “Association for Molecular Pathology Clinical Practice Committee; American College of Medical Genetics Laboratory Quality Assurance Committee: Guidance for fluorescence in situ hybridization testing in hematologic disorders.J Mol Diagn 2007; 9(2):134-43.

Wolff AC, Hammond ME, Schwartz JN, Hagerty KL, Allred DC, Cote RJ, Dowsett M, Fitzgibbons PL, Hanna WM, Langer A, McShane LM, Paik S, Pegram MD, Perez EA, Press MF, Rhodes A, Sturgeon C, Taube SE, Tubbs R, Vance GH, van de Vijver M, Wheeler TM, Hayes DF. “American Society of Clinical Oncology/College of American Pathologists Guideline Recommendations for Human Epidermal growth factor receptor 2 testing in breast cancer.Arch Pathol Lab Med 2007; 131(1): 18..

Wiktor AE, Van Dyke DL, Stupca PJ, Ketterling RP, Thorland EC, Shearer BM, Fink SR, Stockero KJ, Majorowicz JR, Dewald GW. “Preclinical validation of fluorescence in situ hybridization assays for clinical practice.Genet Med 2006; 8(1):16-23.

Brothman AR, Schneider NR, Saikevych I, Cooley LD, Butler MG, Patil S, Mascarello JT, Rao KW, Dewald GW, Park JP, Persons DL, Wolff DJ, Vance GH. “Cytogenetics Resource Committee, College of American Pathologists/American College of Medical Genetics: Cytogenetic heteromorphisms: survey results and reporting practices of Giemsa-band regions that we have pondered for years.Arch Pathol Lab Med 2006; 130(7):947-949.

Persons DL, Tubbs RR, Cooley LD, Dewald GW, Dowling PK, Du E, Mascarello JT, Rao KW, Wilson KS, Wolff DJ, Habegger-Vance G. “HER-2 fluorescence in situ hybridization: results from the survey program of the College of American Pathologists.Arch Pathol Lab Med 2006; 130(3): 325-31.

Mascarello JT, Cooley LD, Davison K, Dewald GW, Brothman AR, Herrman M, Park JP, Persons DL, Rao KW, Schneider NR, Vance GH. Cytogenetics Resource Committee, College of American Pathologists; Cytogenetics Resource Committee “American College of Medical Genetics: Problems with ISCN FISH Nomenclature make it not practical for use in clinical test reports or cytogenetic databases [corrected]Genet Med 2003; 5(5): 370-7. (PDF, 452 K)

Mascarello, JT et al. “As currently formulated, ISCN FISH nomenclature make it not practical for use in clinical test reports or cytogenetic databases.Genetics in Medicine, September/October 2003. (PDF, 452 K)

Clinical Laboratory Assays for HER-2/neu Amplification and Overexpression.” Arch Pathol Lab Med, July 2002: 803-808. (PDF, 514 K)

CAP Proficiency Testing CAP Proficiency Testing

  • Cytogenomic Microarray (CYCGH)
  • Cytogenetics, chromosomal abnormalities (CY)
  • Cytogenetics, validated material (CYM)
  • Fluorescence in situ hybridization (FISH) for Paraffin-Embedded Tissue-
    Brain/Glioma Tissue (CYJ)
    Solid Tumor (CYK)
    Lymphoma (CYL)
  • Fluorescence in situ hybridization (FISH) for constitutional and hematalogic disorders (CYF)
  • Fluorescence in situ hybridization (FISH) for HER2 Gene Amplification (CYH)
  • Fluorescence in situ hybridization (FISH) for Urothelial Cancer Surveillance (CYI)

CY Survey Case Submission Guidelines

View the latest version of guidelines for CY Survey submissions.

CY Case Submission Clinical Info (Word, 30 KB)

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