College of American Pathologists

  Next Generation Sequencing Project Team


Posted October 27, 2014

Reports to: Council of Scientific Affairs

Charge: To advance the adoption of genomic based diagnostics in the clinical community by developing laboratory standards for next generation sequencing and proficiency testing. This project team’s role also encompasses facilitation and development of consensus standards for genomic data interpretation, storage and reporting in collaboration with other professional societies. The project team will also identify pertinent regulatory and standardization issues that arise with the adoption of genomics in clinical practice and recommend potential venues for CAP’s role in creating a solution.

Time Commitment Time Commitment

Number of face-to-face meetings: 3
Length of each meeting: 1.5 days
Typical meeting pattern: Friday/Saturday

Location of meetings: Rotates throughout continental US. One meeting a year is always in Chicago

Number of conference calls: 18–24 per year

Hours of committee work required outside of meetings:
Member: 30 + hours
Chair: 60 + hours

Additional travel or time commitments: Attendance at the CAP annual meeting is strongly encouraged

Activities of Committee Activities of Work Group

  • Develop checklist requirements for next generation sequencing based diagnostics for CAP/CLIA laboratory accreditation
  • Promote genomic based diagnostics by developing standard terminology and tools for interpretation of sequence variants
  • Promote CAP’s role as a leader in Genomic Medicine by speaking at national and international conference on the activities of the committee
  • Collaborate with CDC, NIST, AMP, ACMG, ASCO and other relevant organizations and relevant committees within CAP to promote and develop standards for harmonization of genomic data reporting, transferring genomic information into the electronic health record, and standards for centralized data sharing and curation of sequence variants,
  • Act as advisor to the CAP Board of Governors and other CAP Councils and Committees on issues related to the clinical practice of genomic medicineM