College of American Pathologists
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2010 — January Case of the Month

Updated January 28, 2010


CAP Foundation January 2010 Online Case of the Month

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A 53-year-old man presented with a large soft tissue mass in the chest wall. Tumor infiltration into the lung was demonstrated on CT scan. The resected tumor (16 x 14 x 8 cm) was received with a portion of lung. The cut surface showed a poorly demarcated tan-pink tumor with focal areas of necrosis and multifocal extension to surgical margins. Tumor cells were CD34(+), bcl-2(+), CD99(+) and focally smooth muscle actin(+) and were CD31(-), desmin(-), calretinin(-) and cytokeratin(-).

The master list with the correct answer

  • Desmoplastic mesothelioma
  • Fibrosarcoma
  • Hemangiopericytoma
  • Malignant solitary fibrous tumor (SFT)
  • Monophasic synovial sarcoma

Access Case Critique to view:

  • Appropriate diagnosis
  • Critique
  • References

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