College of American Pathologists

2011 — January Case of the Month

Posted February 10, 2011

CLINICAL SUMMARY: Lymph Node, Mediastinum  

CAP Foundation January 2011 Online Case of the Month

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A 24-year-old woman was involved in a motor vehicle accident. Upon radiological work-up, a large incidental mass was identified in the anterior mediastinum. Excisional biopsy of a single enlarged lymph node was performed.

The master list with the correct answer

  • Angiofollicular hyperplasia (Castleman disease)
  • Follicular lymphoma
  • Lymphocyte-predominant thymoma (WHO type B1)
  • Plasmacytoma
  • Reactive follicular hyperplasia
  • Regressing follicular hyperplasia

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  • Appropriate diagnosis
  • Critique
  • References

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