College of American Pathologists
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2009 — July Case of the Month

Updated June 22, 2009


CAP Foundation July 2009 Online Case of the Month

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An otherwise healthy 21-year-old man presented with a distended abdomen. He had an enlarged spleen with focal hypoechogenic lesions revealed by ultrasonography. Splenectomy was performed. A 28.0 x 15.0 x 4.5 cm, 2100.0 gram spleen contained numerous circumscribed nodules measuring from 0.4 to 4.3 cm in diameter.

The master list with the correct answer

  • Gaucher disease
  • Histiocytic sarcoma
  • Hodgkin lymphoma
  • Interdigitating dendritic cell sarcoma
  • Langerhans cell histiocytosis
  • Sinus histiocytosis with massive lymphadenopathy
    (Rosai-Dorfman disease)

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  • Appropriate diagnosis
  • Critique
  • References

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