College of American Pathologists
CAP Committees & Leadership CAP Calendar of Events Estore CAP Media Center CAP Foundation
 
About CAP    Career Center    Contact Us      
Search: Search
  [Advanced Search]  
 
CAP Home CAP Advocacy CAP Reference Resources and Publications CAP Education Programs CAP Accreditation and Laboratory Improvement CAP Members
CAP Home > Case of the Month > 2010 - Case Archives > Clinical Summary: Spleen

2010 — July Case of the Month

Posted August 30, 2010

CLINICAL SUMMARY: SPLEEN  

CAP Foundation July 2010 Online Case of the Month

View case with:
PC users: ImageScope
First-time use of ImageScope?
* Download (required)

Why use ImageScope?

ImageScope offers many additional features including:

• Ability to view multiple slides
  concurrently; synchronize
  panning/zooming.

• Facility to author annotations.

• Capability to run analysis
  algorithms, and display results.

• Modify image brightness,
  contrast, color balance,
  etc.

• Generally faster and more
  responsive.

MAC/PC Users: WebViewer

A 37-year-old man presented with a 2-month history of unexplained fever and weight loss. He was noted to have pancytopenia, splenomegaly and hepatomegaly. HIV test was negative and no signs of infection were identified. Splenectomy yielded a 2050 gram spleen with diffuse red pulp expansion. Flow cytometric immunophenotypic studies demonstrated a population of medium to large cells expressing CD3 and gamma-delta T-cell receptors. The infiltrate was negative for EBV genomes by in situ hybridization.

The master list with the correct answer

  • Diffuse large B-cell lymphoma
  • Extranodal NK/T cell lymphoma, nasal type
  • Hairy cell leukemia
  • Hepatosplenic T-cell lymphoma
  • Peripheral T-cell lymphoma, unspecified

Access Case Critique to view:

  • Appropriate diagnosis
  • Critique
  • References


Your input is valued - please submit your feedback so that we may continue to optimize this program.

 
 © 2014 College of American Pathologists. All rights reserved. | Terms and Conditions | CAP ConnectFollow Us on FacebookFollow Us on LinkedInFollow Us on TwitterFollow Us on YouTubeFollow Us on FlickrSubscribe to a CAP RSS Feed