College of American Pathologists
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2008 — June Case of the Month

Updated July 1, 2008


CAP Foundation June 2008 Online Case of the Month

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A 65-year-old woman, who had a modified radical mastectomy performed 3 years earlier for breast carcinoma, presented with abdominal distension and altered bowel habits. Following CT-scan of the abdomen and upper and lower GI endoscopy, a colonic biopsy was performed, showing adenocarcinoma with a MUC1(-), ER(-), CDX2(+), CK7(-) and CK20(+) imunophenotype.

The patient developed small intestinal obstruction and a right-hemicolectomy was performed. A right hemicolectomy specimen revealed a circumferential stenosing tumor involving the cecum and the proximal ascending colon. The longitudinal axis of the tumor measured 6.5 cm and the tumor thickness was 2.5 cm.

The master list with the correct answer

  • Goblet cell carcinoid
  • Metastatic carcinoma, breast
  • Metastatic carcinoma, stomach
  • Signet-ring cell carcinoma, primary

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