College of American Pathologists

2010 — May Case of the Month

Posted October 07, 2010


CAP Foundation May 2010 Online Case of the Month

View case with:
PC users: ImageScope
First-time use of ImageScope?
* Download (required)

Why use ImageScope?

ImageScope offers many additional features including:

• Ability to view multiple slides
  concurrently; synchronize

• Facility to author annotations.

• Capability to run analysis
  algorithms, and display results.

• Modify image brightness,
  contrast, color balance,

• Generally faster and more

MAC/PC Users: WebViewer

A 42-year-old man presented with progressive change in personality, confusion, and difficulty walking. MRI of the brain showed diffuse high T2 signal throughout the white matter bilaterally, with only focal enhancement. Following a brain biopsy, he received radiation therapy but declined neurologically and died 30 months after initial diagnosis. At autopsy, the deep cerebral white matter was expanded bilaterally and the gray-white junction was indistinct.

The master list with the correct answer

  • Anaplastic astrocytoma
  • Diffuse fibrillary astrocytoma
  • Glioblastoma
  • Gliomatosis cerebri
  • Oligodendroglioma
  • Radiation necrosis, late-delayed type

Access Case Critique to view:

  • Appropriate diagnosis
  • Critique
  • References

Your input is valued - please submit your feedback so that we may continue to optimize this program.