College of American Pathologists

2011 — May Case of the Month

Posted May 20, 2011


CAP Foundation May 2011 Online Case of the Month

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A 55–year-old woman presented with a recent 20 pound weight loss. The subsequent workup included a CT scan of the abdomen which showed a large right adrenal mass. A right adrenalectomy was performed. The tumor weighed 715 grams and measured 14.0 x 9.5 x 8.0 cm. The cut surface of the tumor was hemorrhagic and necrotic. The tumor cells were synaptophysin (+), chromogranin (-), calretinin (+), CD10 (-), cytokeratin (-).

The master list with the correct answer

  • Adrenal cortical adenoma
  • Adrenal cortical carcinoma
  • Metastatic carcinoma
  • Pheochromocytoma
  • Renal cell carcinoma

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  • Appropriate diagnosis
  • Critique
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