College of American Pathologists

2012 — August Case of the Month

Posted August 29, 2012


CAP Foundation Online Case of the Month

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A previously healthy 62-year-old man presented with massive splenomegaly. Grossly, the spleen was 2,640 g and 27.0 x 19.0 x 7.0 cm and was received with multiple detached lymph nodes and a 1.0 cm in greatest dimension accessory spleen. The cut surface revealed multiple beefy, tan/red, nodules, ranging from 0.1 to 0.3 cm in greatest dimension.

The master list with the correct answer

  • Chronic lymphocytic leukemia/small lymphocytic lymphoma
  • Diffuse large B cell lymphoma
  • Hairy cell leukemia
  • Mantle cell lymphoma
  • Reactive follicular hyperplasia
  • Splenic marginal zone lymphoma

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  • Appropriate diagnosis
  • Critique
  • References

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