College of American Pathologists

2014 — January Case of the Month

Posted January 28, 2014


CAP Foundation Online Case of the Month

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A 24-year-old man with a history of Epstein-Barr virus infection presented with a two- month history of persistent low-grade fever, weight loss, and hepatosplenomegaly. He had anemia and pancytopenia. HIV testing was negative. While undergoing a CT scan the patient suddenly decompensated having a markedly distended abdomen and hypotension. Exploratory laparotomy revealed a ruptured spleen. The 2680 g splenectomy specimen had a homogeneous red-brown cut surface with no definitive masses.

The master list with the correct answer

  • Erdheim Chester disease
  • Langerhans cell histiocytosis
  • Rosai Dorfman disease
  • T-cell lymphoma
  • Viral associated hemophagocytic syndrome

Access Case Critique to view:

  • Appropriate diagnosis
  • Critique
  • References

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