A 24-year-old man with a history of Epstein-Barr virus infection presented with a two- month history of persistent low-grade fever, weight loss, and hepatosplenomegaly. He had anemia and pancytopenia. HIV testing was negative. While undergoing a CT scan the patient suddenly decompensated having a markedly distended abdomen and hypotension. Exploratory laparotomy revealed a ruptured spleen. The 2680 g splenectomy specimen had a homogeneous red-brown cut surface with no definitive masses.
The master list with the correct answer
• Erdheim Chester disease
• Langerhans cell histiocytosis
• Rosai Dorfman disease
• T-cell lymphoma
• Viral associated hemophagocytic syndrome
Access Case Critique to view:
• Appropriate diagnosis
Your input is valued—please submit your feedback
so that we may continue to optimize this program.