A 48-year-old woman with no relevant previous history presented with a right breast mass. A simple mastectomy was performed. Grossly, a 5.0 x 4.8 x 4.0 cm mass well circumscribed mass was present in the retro-areolar region at the junction of the upper outer and inner quadrants. The mass had a tan, homogenous cut surface with “cleft-like” areas grossly visible. Focal gelatinous areas were also seen within the mass. A capsule is identified, but focal areas showed extension of the mass through the capsule into the peri-lesional breast parenchyma. A few satellite nodules were also present in the rest of the breast parenchyma, which appeared to be discrete (non-contiguous) from the larger mass.
The master list with the correct answer
• Malignant fibrous histiocytoma
• Malignant phyllodes tumor
• Mammary-type myofibroblastoma
• Metaplastic carcinoma
• Periductal stromal sarcoma
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• Appropriate diagnosis
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