AP129 A Dozen Diagnostic Dilemmas of the Cervix and Endometrium
8:00–11:30 am
3.0 CME CREDITS
Biopsies and resections of the cervix and endometrium are among the more common specimens seen in pathology practices. While pathologists can generally recognize invasive carcinomas in these sites without great difficulty, the distinction of significant precursor lesions from their benign mimickers remains highly problematic and common. The therapy and prognosis of histologic subtypes of carcinomas in these sites are markedly different, but their histologic distinction may be subtle. Similarly, the diagnostic criteria for some benign processes remain poorly defined. This course will address commonly encountered and highly challenging problems for which textbooks and journal articles often provide insufficient material to permit confident resolution. Faculty will frame each issue as a question and then address the solution in a highly pragmatic fashion.
You will learn to:
- Apply morphologic criteria that can distinguish reactive endocervical lesions from adenocarcinoma in situ, serous from endometrioid adenocarcinoma, and deep glands from minimal deviation adenocarcinoma of the cervix
- Recognize the limitations of determination of depth of myometrial invasion and cervical involvement in endometrial cancer and apply the best practices to their assessment
- Apply a limited panel of immunohistochemical stains to help determine whether an adenocarcinoma has arisen in the endocervix or endometrium
- Optimize intraoperative assessments for endometrial adenocarcinoma
- Recognize features that help distinguish a hydropic abortus from a hydatidiform mole
- Apply a better system for classifying endometritis
Faculty
Richard J. Zaino, MD, FCAP