AP103 Pitfalls in Benign Lymphoid Proliferations: Avoiding an Incorrect Diagnosis of Lymphoma
2:00–5:30 pm
3.0 CME CREDITS
Benign lymphoid proliferations are difficult for the practicing pathologist to diagnose because of significant morphologic and/or clinical overlap with malignant processes. This course addresses specific entities that are often confused or misdiagnosed as lymphoid malignancies, including Epstein-Barr virus infection, Kikuchi lymphadenitis, progressive transformation of germinal centers and follicular hyperplasia, Castleman disease, and marginal/mantle zone hyperplasia. The faculty will discuss each of these entities and identify specific morphologic, clinical, immunophenotypic, and molecular features that may be useful in differentiating between a benign process and a malignant lymphoma. This course will provide a framework for confidently approaching benign lymphoid proliferations and avoiding a misdiagnosis of lymphoma.
You will learn to:
- Diagnose benign lymphoid proliferation
- Utilize cost-effective choices in ancillary test selection for characterizing benign lymphoid proliferations
- Utilize immunophenotyping to differentiate between benign and malignant lymphoid proliferations and identify pitfalls that may be involved in immunophenotypic testing of benign lymphoid proliferations
- Determine when molecular testing may be useful to distinguish benign from malignant lymphoid proliferations and the pitfalls involved in test interpretation
Faculty
Kyle T. Bradley, MD, FCAP
Sherrie L. Perkins, MD, PhD, FCAP