NEW AP132 Application of Molecular Methods in the Diagnosis and Targeted Management of Soft Tissue Neoplasms
1:00–3:00 pm
2.0 CME CREDITS
In this course, faculty will review basic molecular principles related to the development and progression of soft tissue tumors. Histomorphologic and immunophenotypic features of connective tissue neoplasms are discussed in correlation with specific molecular alterations observed in these tumors. The course will emphasize the practical applications of these principles in relation to the appropriate ordering and interpretation of molecular diagnostic tests, integrating theoretical principles with practical applications through presentation of actual clinical cases. Lastly, faculty will discuss current aspects of personalized medicine and the application of advanced molecular testing, utilizing mutational analysis of c-kit in GIST as a model for targeted therapy in soft tissue neoplasms, among other tumors of connective tissues.
You will learn to:
- Describe basic principles of molecular biology of soft tissue tumors
- Recognize different molecular alterations present in common and uncommon tumors of connective tissues
- Apply the above knowledge in the ordering and interpretation of ancillary molecular tests utilized in the diagnosis of soft tissue neoplasms
- Apply current principles related to advanced molecular testing utilized in targeted therapy of soft tissue neoplasms
Faculty
Markku M. Miettinen, MD
Eduardo V. Zambrano, MD, FCAP