CP115 Tandem Mass Spectrometry in Newborn Screening: A Model for the Clinical Pathology Laboratory
1:00–3:00 pm
2.0 CME/CE CREDITS
Mass spectrometry (MS) and tandem mass spectrometry (MS/MS) technologies are rapidly becoming a reality in clinical laboratories. This course will introduce the basic concepts of MS and MS/MS technologies and highlight their use in the field of newborn screening, including hospital preanalytic and postanalytic activities and implementation challenges. Faculty will review newborn screening case studies featuring laboratory and pathological data and then will conclude with a discussion of new applications of MS/MS technology for clinical laboratories (eg, vitamin D, steroid profiling). Attendees will gain a better understanding of the advantages and disadvantages of MS/MS in a clinical setting.
You will learn to:
- Recognize the use of tandem mass spectrometry in newborn screening for detecting multiple metabolic disorders in a single process
- Describe the unique design of the tandem mass spectrometer as a highly specific clinical analyzer
- Contrast advantages and disadvantages of tandem mass spectrometry with conventional technologies such as immunoassay and chromatography
- Identify Clinical and Laboratory Standards Institute (CLSI) guidelines/toolsets for handling preanalytic and postanalytic newborn screening issues
- Explain current and emerging applications of tandem mass spectrometry in the clinical pathology laboratory
Faculty
Ronald J. Whitley, PhD
Cosponsored by 