Short Presentations on Emerging Concepts


The Short Presentations on Emerging Concepts (SPECs) assist pathologists to establish themselves as leaders in personalized medicine and in vivo microscopy (IVM) in their local communities.

Designed for pathologists, these short PowerPoint presentations focus on selected topics:

  • molecular tests that play a key role in patient management that are clinically actionable today
  • educating pathologists colleagues and GI specialist on the role and value of pathologists in IVM

Pathologists will find the Pathology SPECs an especially valuable resource as they facilitate discussion with tumor boards or other physician colleagues.

Member-Only Benefits

Members of the College of American Pathologists (CAP) may log in for complimentary access to the online versions of the SPECs.

Nonmembers may join the CAP to gain access to all member benefits including these SPECs. The printed publication of the molecular SPECs is available for nonmembers for purchase.


The SPEC Book is available as a printed publication with preferred pricing for members:

CAP Members$49, plus shipping and handling
Nonmembers$79, plus shipping and handling

Short Presentations on Emerging Concepts Topics

The following content is updated periodically.

Anatomic Pathology SPECs

  • Colorectal Cancer: Hereditary Nonpolyposis Colorectal Cancer (Lynch Syndrome)
  • Diagnosis and Workup of Thyroid Cancer
  • HER2 Testing in Gastric/GEJ Adenocarcinoma
  • HER2 Testing in Breast Cancer
  • Liquid Biopsy: Circulating Tumor in Cell Free DNA
  • Molecular Genetics of Renal Tumors
  • Molecular Testing for Inherited and Sporadic Colorectal Cancer
  • Molecular Testing in Breast Cancer
  • Next-Generation Sequencing and Cancer Genomics
  • PD-L1: Immune Check Point Blockade in Cancer
  • Therapeutic Guidance for Metastatic Melanoma
  • Workup of Colorectal Cancer
  • Molecular Testing in the Workup of Polycythemia and Thrombocythemia

Clinical Pathology SPECs

  • Diagnosis of Respiratory Viruses
  • Prenatal Screening for Down Syndrome: Past, Present, and Emerging Practices

In Vivo Microscopy SPECs:

  • In Vivo Microscopy(IVM): A New Role for Pathologists
  • Collaboration Between Pathologists and Endoscopists: In Vivo Microscopy (IVM) of the GI Tract
  • Ex Vivo Microscopy(EVM): A New Tool for Pathologists


Hear what other pathologists are saying about the SPECs.

"Concise, timely, well-summarized, and very important information in this early molecular age. "
"Pre-developed educational tools are a big time-saver."