Cancer Protocol Templates

 

New Genitourinary Protocols With WHO Updates Now Available

Seven significantly revised genitourinary cancer protocols are now available with the 7th Edition AJCC TNM Stage Classification. Later this year the CAP will release all of the applicable revised protocols including the genitourinary protocols with the updated 8th Edition AJCC TNM Stage Classification content. Additionally, a new Head and Neck Cancer Biomarker Template is now available.

CAP Cancer Protocol Templates provide guidelines for collecting the essential data elements for complete reporting of malignant tumors and optimal patient care.

The Cancer Biomarker Reporting Templates are intended to provide reporting guidance for commonly ordered biomarkers and are not currently required for accreditation purposes.

Current and previous cancer protocols and cancer biomarker reporting templates can be downloaded using the links in the table below.

Terms of Use

Protocols

Breast
DCIS – Breast
Revised: December 18, 2013
Version: 3.2.0.0
PDF (601 KB)  |  Word (461 KB)  |  2012 Version (357 KB)
Invasive Breast
Revised: January 28, 2016
Version: 3.3.0.0
PDF (930 KB)  |  Word (1 MB)  |  2013 Version (2 MB)
Central Nervous System
Brain/Spinal Cord
Revised: December 2, 2014
Version: 3.1.0.1
PDF (273 KB)  |  Word (206 KB)  |  2013 Version (217 KB)
Endocrine
Adrenal Gland
Revised: October 1, 2013
Version: 3.2.0.0
PDF (858 KB)  |  Word (647 KB)  |  2012 Version (815 KB)
Appendix NET
Revised: October 1, 2013
Version: 3.2.0.1
PDF (774 KB)  |  Word (2.5 MB)  |  2012 Version (513 KB)
Colon NET
Revised: October 1, 2013
Version: 3.2.0.1
PDF (382 KB)  |  Word (266 KB)  |  2012 Version (512 KB)
Pancreas (Endocrine)
Revised: August, 2016
Version: 3.3.0.1
PDF (2.8 MB)  |  Word (1.9 MB)  |  2016 Version (1.2 MB)
Small Intestine NET
Revised: October 1, 2013
Version: 3.3.0.0
PDF (395 KB)  |  Word (270 KB)  |  2012 Version (522 KB)
Stomach NET
Revised: October 1, 2013
Version: 3.3.0.0
PDF (582 KB)  |  Word (2.5 MB)  |  2012 Version (179 KB)
Thyroid
Revised: January 28, 2016
Version: 3.2.0.0
PDF (571 KB)  |  Word (918 KB)  |  2014 Version (2.4 MB)
Gastrointestinal
Ampulla of Vater
Revised: January 28, 2016
Version: 3.2.0.0
PDF (762 KB)  |  Word (972 KB)  |  2013 Version (739 KB)
Anus
Revised: October 1, 2013
Version: 3.2.0.1
PDF (778 KB)  |  Word (1.1 MB)  |  2012 Version (766 KB)
Appendix
Revised: Janaury 28, 2016
Version: 3.4.0.0
PDF (300 KB)  |  Word (105 KB)  |  2013 Version (173 KB)
Colon and Rectum
Revised: January 28, 2016
Version: 3.4.0.0
PDF (1.1 MB)  |  Word (2.3 MB)  |  2013 Version (2.5 MB)
Distal Extrahepatic
Bile Ducts

Revised: August, 2016
Version: 3.6.0.0
PDF (1.1 MB)  |  Word (368 KB) |  2016 Version (416 KB)
Esophagus
Revised: January 28, 2016
Version: 3.2.0.0
PDF (590 KB)  |  Word (4 MB)  |  2013 Version (4.5 MB)
Gallbladder
Revised: October 1, 2013
Version: 3.1.0.2
PDF (967 KB)  |  Word (853 KB)  |  2012 Version (749 KB)
GIST
Revised: December 2, 2014
Version: 3.1.0.0
PDF (1.3 MB)  |  Word (274 KB)  |  2013 Version (1.6 MB)
Hepatocellular Carcinoma
Revised: February 1, 2012
Version: 3.1.0.0
PDF (667 KB)  |  Word (907 KB)  |  2011 Version (378 KB)
Intrahepatic Bile Ducts
Revised: October 1, 2013
Version: 3.1.0.2
PDF (1 MB)  |  Word (2.8 MB)  |  2012 Version (840 KB)
Pancreas (Exocrine)
Revised: August, 2016
Version: 3.4.0.0
PDF (1.4 MB)  |  Word (1.9 MB)  |  2016 Version (1.5 MB)
Perihilar Bile Ducts
Revised: October 1, 2013
Version: 3.1.0.2
PDF (870 KB)  |  Word (2.7 MB KB)  |  2012 Version (448 KB)
Small Intestine
Revised: October 1, 2013
Version: 3.2.0.0
PDF (1.3 MB)  |  Word (1.2 MB)  |  2012 Version (1 MB)
Stomach
Revised: June 11, 2014
Version: 3.3.0.0
PDF (2 MB)  |  Word (3.1 MB)  |  2013 Version (1.4 MB)
Genitourinary
RevisedKidney
Revised: February 28, 2017
Version: 3.3.0.0
PDF (339 KB) | Word (449 KB) | 2012 Version (1.4 MB)
RevisedPenis
Revised: April 3, 2017
Version: 3.3.1.0
PDF (272 KB) | Word (3.9 MB) | 2013 Version (5 MB)
RevisedProstate Gland
Revised: February 28, 2017
Version: 3.3.0.0
PDF (392 KB) | Word (284 KB) | 2012 Version (542 KB)
RevisedTestis
Revised: April 3, 2017
Version: 3.4.1.0
PDF (251 KB) | Word (717 KB) | 2013 Version (760 KB)
RevisedUreter, Renal Pelvis
Revised: February 28, 2017
Version: 1.0.0.0
PDF (251 KB) | Word (328 KB) | 2012 Version (708 KB)
RevisedUrethra
Revised: February 28, 2017
Version: 3.3.0.0
PDF (168 KB) | Word (133 KB) | 2012 Version (183 KB)
RevisedUrinary Bladder
Revised: February 28, 2017
Version: 3.3.0.0
PDF (497 KB) | Word (476 KB) | 2012 Version (225 KB)
Gynecologic
Endometrium
Revised: January 28, 2016
Version: 3.3.0.0
PDF (475 KB)  |  Word (347 KB)  |  2013 Version (678 KB)
Ovary, Fallopian Tube
Published: January 28, 2016
Version: 1.0.0.0
PDF (486 KB)  |  Word (910 KB)  |  2015 Version - Ovary (1.8 MB)
2015 Version - Fallopian Tube (1.8 MB)
Trophoblastic Tumors
Revised: January 28, 2016
Version: 3.1.0.0
PDF (247 KB)  |  Word (131 KB)  |  2013 Version (188 KB)
Uterine Cervix
Revised: January 28, 2016
Version: 3.3.0.0
PDF (297 KB)  |  Word (142 KB)  |  2013 Version (209 KB)
Uterine Sarcoma
Revised: January 28, 2016
Version: 3.1.0.0
PDF (307 KB)  |  Word (271 KB)  |  2013 Version (213 KB)
Vagina
Revised: January 28, 2016
Version: 3.2.0.0
PDF (218 KB)  |  Word (110 KB)  |  2013 Version (161 KB)
Vulva
Revised: January 28, 2016
Version: 3.2.0.0
PDF (226 KB)  |  Word (125 KB)  |  2011 Version (172 KB)
Head and Neck
Larynx
Revised: October 1, 2013
Version: 3.3.0.0
PDF (1.1 MB)  |  Word (1.2 MB)  |  2012 Version (1.2 MB)
Lip and Oral Cavity
Revised: August, 2016
Version: 3.3.0.0
PDF (2.5 MB)  |  Word (1.7 MB)  |  2013 Version (2.5 MB)
Major Salivary Glands
Revised: October 1, 2013
Version: 3.2.0.0
PDF (818 KB)  |  Word (610 KB)  |  2012 Version (771 KB)
Nasal Cavity and Paranasal Sinuses
Revised: October 1, 2013
Version: 3.2.0.0
PDF (528 KB)  |  Word (511 KB)  |  2012 Version (488 KB)
Pharynx
Revised: October 1, 2013
Version: 3.3.0.0
PDF (2.1 MB)  |  Word (2.2 MB)  |  2012 Version (2 MB)
Hematologic
Bone Marrow
Revised: June 15, 2012
Version: 3.0.1.1
PDF (227 KB)  |  Word (454 KB)  |  2011 Version (108 KB)
Hodgkin Lymphoma
Revised: October 1, 2013
Version: 3.1.0.0
PDF (165 KB)  |  Word (90 KB)  |  2012 Version (165 KB)
Non-Hodgkin Lymphoma
Revised: October 1, 2013
Version: 3.2.0.0
PDF (264 KB)  |  Word (132 KB)  |  2012 Version (264 KB)
Ocular Adnexal Lymphoma
Revised: March, 2010
Version: 3.0.0.0
PDF (191 KB)  |  Word (107 KB)  |  2011 Version (134 KB)
Plasma Cell Neoplasms
Published: January 21, 2015
Version: 1.0.0.0
PDF (134 KB)  |  Word (134 KB)
Ophthalmic
Retinoblastoma
Revised: January 28, 2016
Version: 3.2.0.0
PDF (514 KB)  |  Word (387 KB)  |  2013 Version (475 KB)
Uveal Melanoma
Revised: January 28, 2016
Version: 3.3.0.0
PDF (510 KB)  |  Word (296 KB)  |  2013 Version (508 KB)
Pediatric
Ewing Sarcoma
Revised: August 2016, 2012
Version: 3.2.0.0
PDF (724 KB)  |  Word (502 KB)  |  2012 Version (401 KB)
Extragonadal Germ Cell
Revised: August, 2016
Version: 3.1.0.0
PDF (310 KB)  |  Word (127 KB)  |  2011 Version (278 KB)
Hepatoblastoma
Revised: August, 2016
Version: 3.2.0.0
PDF (954 KB)  |  Word (735 KB)  |  2013 Version (212 KB)
Neuroblastoma
Revised: August, 2016
Version: 3.0.0.1
PDF (382 KB)  |  Word (126 KB)  |  2012 Version (238 KB)
Rhabdomyosarcoma
Revised: August, 2016
Version: 3.1.0.0
PDF (274 KB)  |  Word (109 KB)  |  2011 Version (203 KB)
Wilms Tumor
Revised: August, 2016
Version: 3.2.0.0
PDF (241 KB)  |  Word (102 KB)  |  2012 Version (182 KB)
Skin
Melanoma
Revised: January 28, 2016
Version: 3.4.0.0
PDF (693 KB)  |  Word (706 KB)  |  2015 Version (622 KB)
Merkel Cell Carcinoma
Revised: June 15, 2012
Version: 3.0.1.1
PDF (545 KB)  |  Word (543 KB)  |  2011 Version (107 KB)
Squamous Cell Carcinoma
Revised: October 1, 2013
Version: 3.1.0.2
PDF (168 KB)  |  Word (84 KB)  |  2012 Version (159 KB)
Thorax
Heart
Revised: October, 2009
Version: 3.0.0.0
PDF (114 KB)  |  Word (59 KB)  |  2011 Version (84 KB)
Lung
Revised: January 28, 2016
Version: 3.4.0.0
PDF (389 KB)  |  Word (757 KB)  |  2013 Version (1.4 MB)
Pleural Mesothelioma
Revised: February 1, 2011
Version: 3.1.0.0
PDF (135 KB)  |  Word (78 KB)  |  2011 Version (112 KB)
Thymoma and Thymic Carcinoma
Revised: February 1, 2011
Version: 3.1.0.0
PDF (133 KB)  |  Word (72 KB)  |  2011 Version (93 KB)
Other
Bone
Revised: October 1, 2013
Version: 3.1.1.1
PDF (289 KB)  |  Word (223 KB)  |  2011 Version (100 KB)
Peritoneum
Revised: August 19, 2015
Version: 3.2.0.1
PDF (554 KB)  |  Word (2.4 MB)  |  2012 Version (1.3 MB)
Soft Tissue
Revised: October 1, 2013
Version: 3.1.2.0
PDF (233 KB)  |  Word (183 KB)  |  2012 Version (232 KB)

Biomarker Templates

Biomarker Templates are not currently required for accreditation purposes.

Head & Neck
Head & Neck Reporting
Revised: February,28 2017
Version: 1.0.0.0
PDF (163 KB)  |  Word (259 KB)
Breast
Breast Biomarker Reporting
Revised: December 2, 2014
Version: 1.1.0.0
PDF (240 KB)  |  Word (174 KB)  |  2013 Version
CNS
Central Nervous System Biomarker Reporting
Published: December 2, 2014
Version: 1.0.0.0
PDF (992 KB)  |  Word (196 KB)
Endocrine
Thyroid Biomarker Reporting
Revised: June 27, 2016
Version: 1.0.0.1
PDF (137 KB)  |  Word (159 KB)  |  2015 Version (142 KB)
Gastrointestinal
Colon and Rectum Biomarker Reporting
Revised: December 2, 2014
Version: 1.2.0.0
PDF (1.9 MB)  |  Word (105 KB) | 2013 Version (1.6 MB)
GIST Biomarker Reporting
Revised: March 2, 2015
Version: 1.0.0.1
PDF (332 KB)  |  Word (1.5 MB) | 2014 Version (810 KB)
Gastric HER2 Biomarker Reporting
Published: June 11, 2014
Version: 1.0.0.0
PDF (1 MB)  |  Word (58 KB)
Gynecologic
Endometrium Biomarker Reporting
Revised: June 27, 2016
Version: 1.1.0.0
PDF (126 KB)  |  Word (98 KB)  |  2015 Version (133 KB)
Hematologic
Chronic Lymphocytic Leukemia Biomarker Reporting
Revised: July 17, 2015
Version: 1.0.0.1
PDF (1.6 MB)  |  Word (76 KB)  |  2014 Version (1.2 MB)
Chronic Myelogenous Leukemia Biomarker Reporting
Revised: July 17, 2015
Version: 1.0.0.1
PDF (1.6 MB)  |  Word (90 KB)  |  2014 Version (1.2 MB)
Diffuse Large B-Cell Lymphoma Biomarker Reporting
Revised: July 17, 2015
Version: 1.0.0.1
PDF (1.9 MB)  |  Word (90 KB)  |  2014 Version (1.4 MB)
Myeloproliferative Neoplasms Biomarker Reporting
Revised: July 17, 2015
Version: 1.0.0.1
PDF (1.5 MB)  |  Word (84 KB)  |  2014 Version (1.2 MB)
Skin
Melanoma Biomarker Reporting
Revised: July 17, 2015
Version: 1.0.0.1
PDF (97 KB)  |  Word (77 KB)  |  March 2015 Version (113 KB)
Thorax
Lung Biomarker Reporting
Revised: June 27, 2016
Version: 1.3.0.0
PDF (123 KB)  |  Word (2.4 MB)  |  2015 Version (115 KB)

CAP Cancer Protocol Usage Limitations and Copyright

© 2017 College of American Pathologists (CAP). All rights reserved.

The College of American Pathologists (CAP) does not permit reproduction of any substantial portion of these protocols without its written authorization. The CAP hereby authorizes use of these protocols by physicians and other health care providers in reporting on surgical specimens, in teaching, and in carrying out medical research for nonprofit purposes. This authorization does not extend to reproduction or other use of any substantial portion of these protocols for commercial purposes without the written consent of the CAP.

The CAP also authorizes physicians and other health care practitioners to make modified versions of the Protocols solely for their individual use in reporting on surgical specimens for individual patients, teaching, and carrying out medical research for non-profit purposes.

The CAP further authorizes the following uses by physicians and other health care practitioners, in reporting on surgical specimens for individual patients, in teaching, and in carrying out medical research for non-profit purposes: (1) Dictation from the original or modified protocols for the purposes of creating a text-based patient record on paper, or in a word processing document; (2) Copying from the original or modified protocols into a text-based patient record on paper, or in a word processing document; (3) The use of a computerized system for items (1) and (2), provided that the protocol data is stored intact as a single text-based document, and is not stored as multiple discrete data fields.

Other than uses (1), (2), and (3) above, the CAP does not authorize any use of the Protocols in electronic medical records systems, pathology informatics systems, cancer registry computer systems, computerized databases, mappings between coding works, or any computerized system without a written license from the CAP.

Any public dissemination of the original or modified protocols is prohibited without a written license from the CAP.

Used with permission of the American Joint Committee on Cancer (AJCC), Chicago, Illinois. The original and primary source for this information is the AJCC Cancer Staging Manual, Eighth Edition (2016) published by Springer Science+Business Media.

The CAP developed these protocols as an educational tool to assist pathologists in the useful reporting of relevant information. It did not issue the protocols for use in litigation, reimbursement, or other contexts. Nevertheless, the CAP recognizes that the protocols might be used by hospitals, attorneys, payers, and others. Indeed, effective January 1, 2004, the Commission on Cancer of the American College of Surgeons mandated the use of the required data elements of the protocols as part of its Cancer Program Standards for Approved Cancer Programs. Therefore, it becomes even more important for pathologists to familiarize themselves with these documents. At the same time, the CAP cautions that use of the protocols other than for their intended educational purpose may involve additional considerations that are beyond the scope of this document.

The inclusion of a product name or service in a CAP publication should not be construed as an endorsement of such product or service, nor is failure to include the name of a product or service to be construed as disapproval.

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AJCC Cancer Staging Manual Update

The AJCC 8th edition Staging Manual will go into effect January 1, 2018. The CAP will release updated Cancer Protocols and electronic Cancer Checklists (eCC) by the end of the second quarter of 2017.