Cancer Protocol Templates

 


In June 2017, the CAP released 52 updated versions of protocols to reflect changes to tumor staging (8th Edition of the AJCC Tumor Staging Manual). AJCC is not implementing this staging system until January 1st, 2018. We recommend that hospitals and groups start using the updated versions on January 1st, 2018 to ensure that the latest staging information is used. Until then, we recommend that hospitals continue to use the current version of the CAP protocol (with 7th edition staging information) through December 31st, 2017..

CAP Cancer Protocol Templates provide guidelines for collecting the essential data elements for complete reporting of malignant tumors and optimal patient care.

The Cancer Biomarker Reporting Templates are intended to provide reporting guidance for commonly ordered biomarkers and are not currently required for accreditation purposes.

Current and previous cancer protocols and cancer biomarker reporting templates can be downloaded using the links in the table below.

Terms of Use

Protocols

Breast
DCIS – Breast Current Version
PDF (v3.2.0.0)
Word (v3.2.0.0)
December 2013
Previous Version
2012 (v3.1.0.0)
8th Edition AJCC
PDF (v4.0.0.0)
Word (v4.0.0.0)
Use January 1, 2018
Invasive Breast Current Version
PDF (v3.3.0.0)
Word (v3.3.0.0)
January 2016
Previous Version
2013 (v3.2.0.0)
8th Edition AJCC
PDF (v4.0.0.0)
Word (v4.0.0.0)
Use January 1, 2018
Central Nervous System
Brain/Spinal Cord Current Version
PDF (v3.1.0.2)
Word (v3.1.0.2)
December 2014
Previous Version
2014 (v3.1.0.1)
2013 (v3.1.0.0)
Endocrine
Adrenal Gland Current Version
PDF (v3.2.0.0)
Word (v3.2.0.0)
October 2013
Previous Version
2012 (v3.1.0.1)
8th Edition AJCC
PDF (v4.0.1.0)
Word (v4.0.1.0)
Use January 1, 2018
Appendix NET Current Version
PDF (v3.2.0.1)
Word (v3.2.0.1)
October 2013
Previous Version
2012 (v3.2.0.0)
8th Edition AJCC
PDF (v4.0.0.0)
Word (v4.0.0.0)
Use January 1, 2018
Colon NET Current Version
PDF (v3.2.0.1)
Word (v3.2.0.1)
October 2013
Previous Version
2012 (v3.2.0.0)
8th Edition AJCC
PDF (v4.0.0.0)
Word (v4.0.0.0)
Use January 1, 2018
Duodenum and Ampulla NET Previous Version
See Small Intestine NET Protocol
8th Edition AJCC
PDF (v1.0.0.0)
Word (v1.0.0.0)
Use January 1, 2018
Jejunum and Ileum NET Previous Version
See Small Intestine NET Protocol
8th Edition AJCC
PDF (v1.0.0.0)
Word (v1.0.0.0)
Use January 1, 2018
Pancreas (Endocrine) Current Version
PDF (v3.3.0.1)
Word (v3.3.0.1)
August 2013
Previous Version
2016 (v3.3.0.0)
8th Edition AJCC
PDF (v4.0.0.0)
Word (v4.0.0.0)
Use January 1, 2018
Small Intestine NET
(Retired)
Current Version
See Duodenum and Ampulla NET
See Jejunum and Ileum NET
Retired June 2017
Previous Version
2013 (v3.3.0.0)
Stomach NET Current Version
PDF (v3.3.0.0)
Word (v3.3.0.0)
October 2013
Previous Version
2012 (v3.3.0.0)
8th Edition AJCC
PDF (v4.0.0.0)
Word (v4.0.0.0)
Use January 1, 2018
Thyroid Current Version
PDF (v3.2.0.0)
Word (v3.2.0.0)
January 2016
Previous Version
2014 (v3.1.0.0)
8th Edition AJCC
PDF (v4.0.0.0)
Word (v4.0.0.0)
Use January 1, 2018
Gastrointestinal
Ampulla of Vater Current Version
PDF (v3.2.0.0)
Word (v3.2.0.0)
January 2016
Previous Version
2013 (v3.1.0.2)
8th Edition AJCC
PDF (v4.0.0.0)
Word (v4.0.0.0)
Use January 1, 2018
Anus Current Version
PDF (v3.2.0.1)
Word (v3.2.0.1)
October 2013
Previous Version
2012 (v3.2.0.0)
8th Edition AJCC
PDF (v4.0.1.0)
Word (v4.0.1.0)
Use January 1, 2018
Appendix Current Version
PDF (v3.4.0.0)
Word (v3.4.0.0)
January 2016
Previous Version
2013 (v3.3.0.0)
8th Edition AJCC
PDF (v4.0.0.0)
Word (v4.0.0.0)
Use January 1, 2018
Colon and Rectum Current Version
PDF (v3.4.0.0)
Word (v3.4.0.0)
January 2016
Previous Version
2013 (v3.3.0.0)
8th Edition AJCC
PDF (v4.0.0.1)
Word (v4.0.0.1)
Use January 1, 2018
Distal Extrahepatic
Bile Ducts
Current Version
PDF (v3.6.0.0)
Word (v3.6.0.0)
August 2016
Previous Version
2016 (v3.5.0.0)
2013 (v3.4.0.0)
8th Edition AJCC
PDF (v4.0.0.0)
Word (v4.0.0.0)
Use January 1, 2018
Esophagus Current Version
PDF (v3.2.0.0)
Word (v3.2.0.0)
January 2016
Previous Version
2013 (v3.1.1.2)
8th Edition AJCC
PDF (v4.0.0.0)
Word (v4.0.0.0)
Use January 1, 2018
Gallbladder Current Version
PDF (v3.1.0.2)
Word (v3.1.0.2)
October 2013
Previous Version
2012 (v3.1.0.1)
8th Edition AJCC
PDF (v4.0.0.0)
Word (v4.0.0.0)
Use January 1, 2018
GIST Current Version
PDF (v3.1.0.0)
Word (v3.1.0.0)
December 2014
Previous Version
2013 (v3.0.2.2)
8th Edition AJCC
PDF (v4.0.0.1)
Word (v4.0.0.1)
Use January 1, 2018
Hepatocellular Carcinoma Current Version
PDF (v3.1.0.0)
Word (v3.1.0.0)
February 2011
  8th Edition AJCC
PDF (v4.0.0.0)
Word (v4.0.0.0)
Use January 1, 2018
Intrahepatic Bile Ducts Current Version
PDF (v3.1.0.2)
Word (v3.1.0.2)
October 2013
Previous Version
2012 (v3.1.0.1)
8th Edition AJCC
PDF (v4.0.0.0)
Word (v4.0.0.0)
Use January 1, 2018
Pancreas (Exocrine) Current Version
PDF (v3.4.0.0)
Word (v3.4.0.0)
August 2016
Previous Version
2016 (v3.3.0.0)
2013 (v3.2.0.1)
8th Edition AJCC
PDF (v4.0.0.0)
Word (v4.0.0.0)
Use January 1, 2018
Perihilar Bile Ducts Current Version
PDF (v3.1.0.2)
Word (v3.1.0.2)
October 2013
Previous Version
2012 (v3.1.0.1)
8th Edition AJCC
PDF (v4.0.0.0)
Word (v4.0.0.0)
Use January 1, 2018
Small Intestine Current Version
PDF (v3.2.0.0)
Word (v3.2.0.0)
October 2013
Previous Version
2012 (v3.1.0.2)
8th Edition AJCC
PDF (v4.0.0.0)
Word (v4.0.0.0)
Use January 1, 2018
Stomach Current Version
PDF (v3.3.0.0)
Word (v3.3.0.0)
June 2014
Previous Version
2013 (v3.2.0.1)
8th Edition AJCC
PDF (v4.0.0.0)
Word (v4.0.0.0)
Use January 1, 2018
Genitourinary
Kidney Current Version
PDF (v3.3.0.0)
Word (v3.3.0.0)
February 2017
Previous Version
2013 (v3.2.0.0)
8th Edition AJCC
PDF (v4.0.1.0)
Word (v4.0.1.0)
Use January 1, 2018
Penis Current Version
PDF (v3.3.1.0)
Word (v3.3.1.0)
February 2017
Previous Version
2013 (v3.2.0.0)
8th Edition AJCC
PDF (v4.0.1.0)
Word (v4.0.1.0)
Use January 1, 2018
Prostate Gland Current Version
PDF (v3.3.0.0)
Word (v3.3.0.0)
February 2017
Previous Version
2012 (v3.2.0.0)
8th Edition AJCC
PDF (v4.0.1.0)
Word (v4.0.1.0)
Use January 1, 2018
Testis Current Version
PDF (v3.4.1.0)
Word (v3.4.1.0)
February 2017
Previous Version
2013 (v3.3.0.0)
8th Edition AJCC
PDF (v4.0.1.0)
Word (v4.0.1.0)
Use January 1, 2018
Ureter, Renal Pelvis Current Version
PDF (v1.0.0.0)
Word (v1.0.0.0)
February 2017
Previous Version
2013 (v3.4.0.0)
8th Edition AJCC
PDF (v2.1.0.0)
Word (v2.1.0.0)
Use January 1, 2018
Urethra Current Version
PDF (v3.3.0.0)
Word (v3.3.0.0)
February 2017
Previous Version
2012 (v3.2.1.0)
8th Edition AJCC
PDF (v4.0.1.0)
Word (v4.0.1.0)
Use January 1, 2018
Urinary Bladder Current Version
PDF (v3.3.0.0)
Word (v3.3.0.0)
February 2017
Previous Version
2012 (v3.2.1.0)
8th Edition AJCC
PDF (v4.0.1.0)
Word (v4.0.1.0)
Use January 1, 2018
Gynecologic
Endometrium Current Version
PDF (v3.3.0.0)
Word (v3.3.0.0)
January 2016
Previous Version
2013 (v3.2.0.1)
8th Edition AJCC
PDF (v4.0.0.0)
Word (v4.0.0.0)
Use January 1, 2018
Ovary, Fallopian Tube, Peritoneum Current Version
2016 Ovary, Fallopian Tube (v1.0.0.0)
2015 Peritoneum (v3.2.0.1)
January 2016
Previous Versions
2015 Ovary (v3.2.0.1)
2015 Fallopian Tube (v3.1.0.2)
8th Edition AJCC
PDF (v1.0.0.0)
Word (v1.0.0.0)
Use January 1, 2018
Trophoblastic Tumors Current Version
PDF (v3.1.0.0)
Word (v3.1.0.0)
January 2016
Previous Version
2013 (v3.0.0.3)
8th Edition AJCC
PDF (v4.0.0.0)
Word (v4.0.0.0)
Use January 1, 2018
Uterine Cervix Current Version
PDF (v3.3.0.0)
Word (v3.3.0.0)
January 2016
Previous Version
2013 (v3.2.1.0)
8th Edition AJCC
PDF (v4.0.0.1)
Word (v4.0.0.1)
Use January 1, 2018
Uterine Sarcoma Current Version
PDF (v3.1.0.0)
Word (v3.1.0.0)
January 2016
Previous Version
2013 (v3.0.0.0)
8th Edition AJCC
PDF (v4.0.0.0)
Word (v4.0.0.0)
Use January 1, 2018
Vagina Current Version
PDF (v3.2.0.0)
Word (v3.2.0.0)
January 2016
Previous Version
2013 (v3.1.0.3)
8th Edition AJCC
PDF (v4.0.0.1)
Word (v4.0.0.1)
Use January 1, 2018
Vulva Current Version
2016 (v3.2.0.0)
Word (v3.2.0.0)
January 2016
Previous Version
2012 (v3.1.0.1)
8th Edition AJCC
PDF (v4.0.0.1)
Word (v4.0.0.1)
Use January 1, 2018
Head and Neck
Larynx Current Version
PDF (v3.3.0.0)
Word(v3.3.0.0)
October 2013
Previous Version
2012 (v3.2.0.0)
8th Edition AJCC
PDF (v4.0.0.0)
Word v4.0.0.0)
Use January 1, 2018
Lip and Oral Cavity Current Version
PDF (v3.3.0.0)
Word (v3.3.0.0)
August 2016
Previous Version
2013 (v3.2.0.0)
8th Edition AJCC
PDF (v4.0.0.0)
Word (v4.0.0.0)
Use January 1, 2018
Major Salivary Glands Current Version
PDF (v3.2.0.0)
Word (v3.2.0.0)
October 2013
Previous Version
2012 (v3.1.0.2)
8th Edition AJCC
PDF (v4.0.0.0)
Word (v4.0.0.0)
Use January 1, 2018
Nasal Cavity and Paranasal Sinuses Current Version
PDF (v3.2.0.0)
Word(v3.2.0.0)
October 2013
Previous Version
2012 (v3.1.0.1)
8th Edition AJCC
PDF (v4.0.0.0)
Word (v4.0.0.0)
Use January 1, 2018
Pharynx Current Version
PDF (v3.3.0.0)
Word (v3.3.0.0)
October 2013
Previous Version
2012 (v3.2.0.0)
8th Edition AJCC
PDF (v4.0.0.0)
Word (v4.0.0.0)
Use January 1, 2018
Hematologic
Bone Marrow Current Version
PDF (v3.0.1.2)
Word (v3.0.1.2)
June 2012
Previous Version
2012 (v3.0.1.1)
Hodgkin Lymphoma Current Version
PDF (v3.1.0.1)
Word (v3.1.0.1)
October 2013
Previous Version
2013 (v3.1.0.0)
2012 (v3.0.0.0)
Non-Hodgkin Lymphoma Current Version
PDF (v3.2.0.1)
Word (v3.2.0.1)
October 2013
Previous Version
2013 (v3.2.0.0)
Ocular Adnexal Lymphoma
(Retired)
Current Version
No longer required for accreditation as of September 2017
Previous Version
PDF (v3.0.0.0)
Word (v3.0.0.0)
March 2010
Retired September 2017
Plasma Cell Neoplasms Current Version
PDF (v1.0.0.1)
Word (v1.0.0.1)
January 2015
Previous Version
2015 (v1.0.0.0)
Ophthalmic
Retinoblastoma Current Version
PDF (v3.2.0.0)
Word
January 2016
Previous Version
2013 (v3.1.0.0)
8th Edition AJCC
PDF (v4.0.0.0)
Word (v4.0.0.0)
Use January 1, 2018
Uveal Melanoma Current Version
PDF (v3.3.0.0)
Word (v3.3.0.0)
January 2016
Previous Version
2013 (v3.2.0.0)
8th Edition AJCC
PDF (v4.0.0.0)
Word (v4.0.0.0)
Use January 1, 2018
Pediatric
Ewing Sarcoma Current Version
PDF (v3.2.0.1)
Word (v3.2.0.1)
August 2016
Previous Version
2016 (v3.2.0.0)
2012 (v3.1.0.2)
 
Extragonadal Germ Cell Current Version
PDF (v3.1.0.1)
Word (v3.1.0.1)
August 2016
Previous Version
2016 (v3.1.0.0)
2011 (v3.0.0.1)
 
Hepatoblastoma Current Version
PDF (v3.2.0.1)
Word (v3.2.0.1)
August 2016
Previous Version
2016 (v3.2.0.0)
2013 (v3.1.1.1)
 
Neuroblastoma Current Version
PDF (v3.1.0.1)
Word (v3.1.0.1)
August 2016
Previous Version
2016 (v3.1.0.0)
2012 (v3.0.0.1)
 
Rhabdomyosarcoma Current Version
PDF (v3.2.0.1)
Word (v3.2.0.1)
August 2016
Previous Version
2106 (v3.2.0.0)
2011 (v3.1.0.0)
 
Wilms Tumor Current Version
PDF (v3.2.0.1)
Word (v3.2.0.1)
August 2016
Previous Version
2016 (v3.2.0.0)
2012 (v3.1.0.2)
 
Skin
Melanoma Current Version
PDF (v3.4.0.0)
Word (v3.4.0.0)
January 2016
Previous Version
2015 (v3.3.0.1)
8th Edition AJCC
PDF (v4.0.0.0)
Word (v4.0.0.0)
Use January 1, 2018
Merkel Cell Carcinoma Current Version
PDF (v3.0.1.1)
Word (v3.0.1.1)
June 2012
8th Edition AJCC
PDF (v4.0.0.0)
Word (v4.0.0.0)
Use January 1, 2018
Squamous Cell Carcinoma
(Retired)
Current Version
No longer required for accreditation as of July 2017. Use of this protocol for cutaneous squamous carcinomas other than penis and vulva is optional.

PDF (v3.1.0.2)
Word (v3.1.0.2)
October 2013
Retired June 2017
8th Edition AJCC
See site-specific Cancer Protocols (e.g. Penis, Vulva, Head & Neck) for AJCC 8th edition reporting in 2018
Thorax
Heart
(Retired)
Current Version
No longer required for accreditation as of July 2017
Previous Version
PDF (v3.0.0.0)
Word (v3.0.0.0)
October 2009
Retired June 2017
8th Edition AJCC
Not Applicable
Lung Current Version
PDF (v3.4.0.0)
Word (v3.4.0.0)
January 2016
Previous Version
2013 (v3.3.0.0)
8th Edition AJCC
PDF (v4.0.0.1)
Word (v4.0.0.1)
Use January 1, 2018
Pleural Mesothelioma Current Version
PDF (v3.1.0.0)
Word (v3.1.0.0)
February 2011
8th Edition AJCC
PDF (v4.0.0.0)
Word (v4.0.0.0)
Use January 1, 2018
Thymus Current Version
PDF (v3.1.0.0)
Word (v3.1.0.0)
February 2011
8th Edition AJCC
PDF (v4.0.0.0)
Word (v4.0.0.0)
Use January 1, 2018
Other
Bone Current Version
PDF (v3.1.1.1)
Word (v3.1.1.1)
October 2013
8th Edition AJCC
PDF (v4.0.0.0)
Word (v4.0.0.0)
Use January 1, 2018
Peritoneum Current Version
See Ovary, Fallopian Tube, Peritoneum
June 2017
Previous Version
2015 (v3.2.0.1)
2012 (v3.1.0.0)
Previous Versions
Soft Tissue Current Version
PDF (v3.1.2.0)
Word (v3.1.2.0)
October 2013
Previous Version
2012 (3.1.1.0)
8th Edition AJCC
PDF (v4.0.0.0)
Word (v4.0.0.0)
Use January 1, 2018

Biomarker Templates

Biomarker Templates are not currently required for accreditation purposes.

Head & Neck
Head & Neck Reporting Current Version
PDF (v1.0.0.0)
Word (v1.0.0.0)
February 2017
Breast
Breast Biomarker Reporting Current Version
PDF (v1.1.0.0)
Word (v1.1.0.0)
December 2014
Previous Version
2013 (v1.0.0.0)
CNS
Central Nervous System Biomarker Reporting Current Version
PDF (v1.1.0.0)
Word (v1.1.0.0)
December 2014
Endocrine
Thyroid Biomarker Reporting Current Version
PDF (v1.0.0.1)
Word (v1.0.0.1)
June 2016
Previous Version
2015 (v1.0.0.0)
Gastrointestinal
Colon and Rectum Biomarker Reporting Current Version
PDF (v1.2.0.0)
Word (v1.2.0.0)
December 2014
Previous Version
2013 (v1.0.0.0)
GIST Biomarker Reporting Current Version
PDF (v1.0.0.1)
Word (v1.0.0.1)
March 2015
Previous Version
2014 (v1.0.0.0)
Gastric HER2 Biomarker Reporting Current Version
PDF (v1.0.0.1)
Word (v1.0.0.1)
June 2017
Previous Version
2014 (v1.0.0.0)
Gynecologic
Endometrium Biomarker Reporting Current Version
PDF (v1.1.0.0)
Word (v1.1.0.0)
June 2016
Previous Version
2015 (v1.0.0.0)
Hematologic
Chronic Lymphocytic Leukemia Biomarker Reporting Current Version
PDF (v1.0.0.2)
Word (v1.0.0.2)
July 2015
Previous Version
2015 (v1.0.0.1)
2014 (v1.0.0.0)
Chronic Myelogenous Leukemia Biomarker Reporting Current Version
PDF (v1.0.0.2)
Word (v1.0.0.2)
July 2015
Previous Version
2015 (v1.0.0.1)
2014 (v1.0.0.0)
Diffuse Large B-Cell Lymphoma Biomarker Reporting Current Version
PDF (v1.0.0.2)
Word (v1.0.0.2)
July 2015
Previous Version
2015 (v1.0.0.1)
2014 (v1.0.0.0)
Myeloproliferative Neoplasms Biomarker Reporting Current Version
PDF (v1.0.0.2)
Word (v1.0.0.2)
July 2015
Previous Version
2015 (v1.0.0.1)
2014 (v1.0.0.0)
Skin
Melanoma Biomarker Reporting Current Version
PDF (v1.0.0.1)
Word (v1.0.01)
July 2015
Previous Version
2015 (v1.0.0.0)
Thorax
Lung Biomarker Reporting Current Version
PDF (v1.3.0.1)
Word (v1.3.0.1)
June 2016
Previous Version
2015 (v1.2.0.0)

CAP Cancer Protocol Usage Limitations and Copyright

© 2017 College of American Pathologists (CAP). All rights reserved.

The College of American Pathologists (CAP) does not permit reproduction of any substantial portion of these protocols without its written authorization. The CAP hereby authorizes use of these protocols by physicians and other health care providers in reporting on surgical specimens, in teaching, and in carrying out medical research for nonprofit purposes. This authorization does not extend to reproduction or other use of any substantial portion of these protocols for commercial purposes without the written consent of the CAP.

The CAP also authorizes physicians and other health care practitioners to make modified versions of the Protocols solely for their individual use in reporting on surgical specimens for individual patients, teaching, and carrying out medical research for non-profit purposes.

The CAP further authorizes the following uses by physicians and other health care practitioners, in reporting on surgical specimens for individual patients, in teaching, and in carrying out medical research for non-profit purposes: (1) Dictation from the original or modified protocols for the purposes of creating a text-based patient record on paper, or in a word processing document; (2) Copying from the original or modified protocols into a text-based patient record on paper, or in a word processing document; (3) The use of a computerized system for items (1) and (2), provided that the protocol data is stored intact as a single text-based document, and is not stored as multiple discrete data fields.

Other than uses (1), (2), and (3) above, the CAP does not authorize any use of the Protocols in electronic medical records systems, pathology informatics systems, cancer registry computer systems, computerized databases, mappings between coding works, or any computerized system without a written license from the CAP.

Any public dissemination of the original or modified protocols is prohibited without a written license from the CAP.

Used with permission of the American Joint Committee on Cancer (AJCC), Chicago, Illinois. The original and primary source for this information is the AJCC Cancer Staging Manual, Eighth Edition (2016) published by Springer Science+Business Media.

The CAP developed these protocols as an educational tool to assist pathologists in the useful reporting of relevant information. It did not issue the protocols for use in litigation, reimbursement, or other contexts. Nevertheless, the CAP recognizes that the protocols might be used by hospitals, attorneys, payers, and others. Indeed, effective January 1, 2004, the Commission on Cancer of the American College of Surgeons mandated the use of the required data elements of the protocols as part of its Cancer Program Standards for Approved Cancer Programs. Therefore, it becomes even more important for pathologists to familiarize themselves with these documents. At the same time, the CAP cautions that use of the protocols other than for their intended educational purpose may involve additional considerations that are beyond the scope of this document.

The inclusion of a product name or service in a CAP publication should not be construed as an endorsement of such product or service, nor is failure to include the name of a product or service to be construed as disapproval.

Back to the top

 


Revised Cancer Protocols and Electronic Cancer Checklists now available

The revised protocols now incorporate changes to tumor stage classification from the AJCC 8th edition Cancer Staging Manual and updated WHO classifications.