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- Monkeypox alert: New cases in Southern California
Three unrelated cases of clade I monkeypox virus were found in Southern California, suggesting a potential community spread in the US.
Zoom In: The CDC reports that the cases have no travel history or common exposure, indicating possible local transmission, and continues to assess the risk of clade I MPXV to the US general population as low.
State, local, and territorial public health authorities should promptly report cases to CDC, including orthopoxvirus generic (ie, non-variola orthopoxvirus) positive and clade II negative test results from patients.
- Increased surveillance and investigations are ongoing, with no additional cases identified so far.
- The CDC’s current clade typing is limited due to resource constraints.
- Non-CDC labs should notify state health departments if clade I MPXV is detected.
Guidance for clinicians:
- Be aware of MPXV symptoms and inquire about patient travel history and risk factors.
- Report suspected cases to local and state public health authorities immediately.
- Consider MPXV testing and vaccination as recommended by the CDC.
Additional resources: Check HAN Health Update 516 for the latest CDC guidance and travel advisories.