In vivo microscopy (IVM) allows the microscopic evaluation of tissue without the tissue being excised. Potential applications of IVM include obtaining microscopic information from areas that are difficult to sample (for example, eye, brain, coronary arteries) and guiding biopsy locations in organs with lumens such that the sampled tissue is more likely to contain diagnostic tissue, while potentially decreasing the total number of biopsies needed to make a correct diagnosis. As IVM technologies are increasingly being incorporated in clinical practice, pathologists are presented with a unique opportunity to transform medicine.
- Discuss the emerging clinical applications of IVM that are relevant to pathologists’ practice.
- Discuss the roles and opportunities that IVM could have on the practice of pathology.
Hany Osman, MD