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- Molecular Oncology Topic Center
The CAP Molecular Oncology Committee publishes manuscripts about laboratory quality and performance utilizing data derived from proficiency testing supported by the committee. The following manuscripts were authored by members of the Molecular Oncology Committee:
- SPOT/Dx Pilot Reanalysis and College of American Pathologists Proficiency Testing for KRAS and NRAS Demonstrate Excellent Laboratory Performance
Arch Pathol Lab Med 2023
Ahmet Zehir, Valentina Nardi, Eric Q. Konnick, Christina M. Lockwood, Thomas A. Long, Nikoletta Sidiropoulos, Rhona J. Souers, Patricia Vasalos, Neal I. Lindeman, Joel T. Moncur - RNA Sequencing for Solid Tumor Fusion Gene Detection: Proficiency Testing Practice and Performance Comparison
Arch Pathol Lab Med 2023
Julia A. Bridge, Kevin C. Halling, Joel T. Moncur, Rhona J. Souers, Meera R. Hameed, Helen Fernandes, Angshumoy Roy, Lea Surrey, Laura J. Tafe, Patricia Vasalos, Dolores H. Lopez-Terrada - In Silico Approaches to Proficiency Testing: Considerations for Continued Feasibility
Journal of Molecular Diagnostics 2023
Ian S. Hagemann, Ahmet Zehir, Carlos J. Suarez, Larissa V. Furtado, Jaimie Halley, Megan Kane, Nicole Mot, Patricia Vasalos, Joel T. Moncur, Eric Q. Konnick - Current Laboratory Testing Practices for Assessment of ERBB2/HER2 in Endometrial Serous Carcinoma and Colorectal Carcinoma
Arch Pathol Lab Med 2022
Ian S. Hagemann, Julia A. Bridge, Laura J. Tafe, Meera R. Hameed, Joel T. Moncur, Andrew M. Bellizzi, Michelle Dolan, Patricia Vasalos, Megan E. Kane, Rhona J. Souers, Anna Yemelyanova - Clinical Laboratory Testing Practices in Diffuse Gliomas Prior to Publication of 2021 World Health Organization Classification of Central Nervous System Tumors
Arch Pathol Lab Med 2022
Shakti H. Ramkissoon, Helen Fernandes, Dolores H. Lopez-Terrada, Meera R. Hameed, Dimitri G. Trembath, Julia A. Bridge, Neal I. Lindeman, Rhona J. Souers, Patricia Vasalos, Daniel J. Brat, Joel T. Moncur - Clinical Testing for Tumor Cell-Free DNA: College of American Pathologists' Proficiency Programs Reveal Practice Trends
Arch Pathol Lab Med 2022
Kelly A. Devereaux, Rhona J. Souers, Jason D. Merker, Neal I. Lindeman, Rondell P. Graham, Meera R. Hameed, Patricia Vasalos, Joel T. Moncur, Christina M. Lockwood, Rena R. Xian - Four-Year Laboratory Performance of the First College of American Pathologists In Silico Next-Generation Sequencing Bioinformatics Proficiency Testing Surveys
Arch Pathol Lab Med 2022
Larissa V. Furtado, Rhona J. Souers, Patricia Vasalos, Jaimie G. Halley, Dara L. Aisner, Rakesh Nagarajan, Karl V. Voelkerding, Jason D. Merker, Eric Q. Konnick - Most Frequently Cited Accreditation Inspection Deficiencies for Clinical Molecular Oncology Testing Laboratories and Opportunities for Improvement
Arch Pathol Lab Med 2022
Authors: Nikoletta Sidiropoulos, Sarah K. Daley, Marian Briggs, Helen Fernandes, Christina M. Lockwood, Amer Z. Mahmoud, Jason D. Merker, Patricia Vasalos, Lynnette M. Wielgos, Joel T. Moncur, Daniel H. Farkas - Neoplastic Cellularity Assessment in Molecular Testing: A Multi-institutional Practice Survey and Performance Challenge Identifies a Need for Standardization
Arch Pathol Lab Med 2022
Authors: Kelly A. Devereaux, Rhona J. Souers, Rondell P. Graham, Bryce P. Portier, Lea F. Surrey, Anna Yemelyanova, Patricia Vasalos, Dimitri G. Trembath, Joel T. Moncur - Tiered Somatic Variant Classification Adoption Has Increased Worldwide With Some Practice Differences Based on Location and Institutional Setting: A Study From the College of American Pathologists Molecular Oncology Committee
Arch Pathol Lab Med 2022
Authors: Frido K. Bruehl, Annette S. Kim, Marilyn M. Li, Neal I. Lindeman, Joel T. Moncur, Rhona J. Souers, Patricia Vasalos, Karl V. Voelkerding, Rena R. Xian, Lea F. Surrey - Next-Generation Sequencing Somatic and Germline Assay Troubleshooting Guide Derived From Proficiency Testing Data
Arch Pathol Lab Med 2021
Authors: Valentina Nardi, Karen D. Tsuchiya, Annette S. Kim, Lora J. H. Bean, Jaimie G. Halley, Thomas A. Long, Szabolcs Szelinger, Patricia Vasalos, John A. Thorson, Ann M. Moyer, Joel T. Moncur - An Overview of Characteristics of Clinical Next-Generation Sequencing–Based Testing for Hematologic Malignancies
Arch Pathol Lab Med 2021
Authors: Bing M. Zhang, Alissa Keegan, Peng Li, Neal I. Lindeman, Rakesh Nagarajan, Mark J. Routbort, Patricia Vasalos, Annette S. Kim, Jason D. Merker - Proficiency Testing of Standardized Samples Shows High Interlaboratory Agreement for Clinical Next-Generation Sequencing–Based Hematologic Malignancy Assays With Survey Material–Specific Differences in Variant Frequencies
Arch Pathol Lab Med 1 August 2020; 144 (8): 959–966
Authors: Alissa Keegan, Julia A. Bridge, Neal I. Lindeman, Thomas A. Long, Jason D. Merker, Joel T. Moncur, Nathan D. Montgomery, Rakesh Nagarajan, Paul G. Rothberg, Mark J. Routbort, Patricia Vasalos, Rena Xian, Annette S. Kim - Comparative Performance of High-Risk Human Papillomavirus RNA and DNA In Situ Hybridization on College of American Pathologists Proficiency Tests
Arch Pathol Lab Med 1 March 2020; 144 (3): 344–349
Authors: Elaine S. Keung, Rhona J. Souers, Julia A. Bridge, William C. Faquin, Rondell P. Graham, Meera R. Hameed, James S. Lewis, Jason D. Merker, Patricia Vasalos, Joel T. Moncur - Performance Comparison of Different Analytic Methods in Proficiency Testing for Mutations in the BRAF, EGFR, and KRAS Genes: A Study of the College of American Pathologists Molecular Oncology Committee
Arch Pathol Lab Med 1 October 2019; 143 (10): 1203–1211
Authors: Joel T. Moncur, Angela N. Bartley, Julia A. Bridge, Suzanne Kamel-Reid, Alexander J. Lazar, Neal I. Lindeman, Thomas A. Long, Jason D. Merker, Alex J. Rai, David L. Rimm, Paul G. Rothberg, Patricia Vasalos, Annette S. Kim - Next-Generation Sequencing (NGS) Methods Show Superior or Equivalent Performance to Non-NGS Methods on BRAF, EGFR, and KRAS Proficiency Testing Samples
Arch Pathol Lab Med 1 August 2019; 143 (8): 980–984
Authors: Lea F. Surrey, Fredrick D. Oakley, Jason D. Merker, Thomas A. Long, Patricia Vasalos, Joel T. Moncur, Annette S. Kim - Proficiency Testing of Standardized Samples Shows Very High Interlaboratory Agreement for Clinical Next-Generation Sequencing–Based Oncology Assays
Arch Pathol Lab Med 1 April 2019; 143 (4): 463–471
Authors: Jason D. Merker, Kelly Devereaux, A. John Iafrate, Suzanne Kamel-Reid, Annette S. Kim, Joel T. Moncur, Stephen B. Montgomery, Rakesh Nagarajan, Bryce P. Portier, Mark J. Routbort, Craig Smail, Lea F. Surrey, Patricia Vasalos, Alexander J. Lazar, Neal I. Lindeman - Comparative Performance of Breast Cancer Human Epidermal Growth Factor Receptor 2 Fluorescence In Situ Hybridization and Brightfield In Situ Hybridization on College of American Pathologists Proficiency Tests
Arch Pathol Lab Med 1 October 2018; 142 (10): 1254–1259
Authors: Katherine B. Geiersbach, Julia A. Bridge, Michelle Dolan, Lawrence J. Jennings, Diane L. Persons, Rhona J. Souers, Karen D. Tsuchiya, Patricia H. Vasalos, Joel T. Moncur - Circulating Tumor DNA Analysis in Patients With Cancer: American Society of Clinical Oncology and College of American Pathologists Joint Review
Arch Pathol Lab Med 1 October 2018; 142 (10): 1242–1253
Authors: Jason D. Merker, Geoffrey R. Oxnard, Carolyn Compton, Maximilian Diehn, Patricia Hurley, Alexander J. Lazar, Neal Lindeman, Christina M. Lockwood, Alex J. Rai, Richard L. Schilsky, Apostolia M. Tsimberidou, Patricia Vasalos, Brooke L. Billman, Thomas K. Oliver, Suanna S. Bruinooge, Daniel F. Hayes, Nicholas C. Turner - Comparison of Laboratory-Developed Tests and FDA-Approved Assays for BRAF, EGFR, and KRAS Testing.
JAMA Oncol. June 2018;4(6):838–841.
Authors: Annette Kim, Angela N. Bartley, Julia A. Bridge, Suzanne Kamel-Reid, Alexander J. Lazar, Neal I. Lindeman, Thomas A. Long, Jason D. Merker, Alex J. Rai, David L. Rimm, Paul G. Rothberg, Patricia Vasalos, Joel T. Moncur - A Window Into Clinical Next-Generation Sequencing–Based Oncology Testing Practices
Arch Pathol Lab Med 1 December 2017; 141 (12): 1679–1685
Authors: Rakesh Nagarajan, Angela N. Bartley, Julia A. Bridge, Lawrence J. Jennings, Suzanne Kamel-Reid, Annette Kim, Alexander J. Lazar, Neal I. Lindeman, Joel Moncur, Alex J. Rai, Mark J. Routbort, Patricia Vasalos, Jason D. Merker - Worldwide Frequency of Commonly Detected EGFR Mutations
Arch Pathol Lab Med 1 February 2018; 142 (2): 163–167
Authors: Rondell P. Graham, Amanda L. Treece, Neal I. Lindeman, Patricia Vasalos, Mu Shan, Lawrence J. Jennings, David L. Rimm - Reporting Results of Molecular Tests: A Retrospective Examination of BRAF Mutation Reporting
Arch Pathol Lab Med 1 May 2017; 141 (5): 658–665
Authors: Amanda L. Treece, Margaret L. Gulley, Patricia Vasalos, Cherie Paquette, Neal I. Lindeman, Lawrence J. Jennings, Angela N. Bartley - Summary of Microsatellite Instability Test Results From Laboratories Participating in Proficiency Surveys: Proficiency Survey Results From 2005 to 2012
Arch Pathol Lab Med 1 March 2014; 138 (3): 363–370
Authors: Theresa A. Boyle, Julia A. Bridge, Linda M. Sabatini, Jan A. Nowak, Patricia Vasalos, Lawrence J. Jennings, Kevin C. Halling, and the College of American Pathologists Molecular Oncology Committee - A Prospective, Multi-Institutional Diagnostic Trial to Determine Pathologist Accuracy in Estimation of Percentage of Malignant Cells
Arch Pathol Lab Med 1 November 2013; 137 (11): 1545–1549
Authors: Hollis Viray, Kevin Li, Thomas A. Long, Patricia Vasalos, Julia A. Bridge, Lawrence J. Jennings, Kevin C. Halling, Meera Hameed, David L. Rimm