Hematopathology is defined by the Accreditation Council for Graduate Medical Education as the practice of pathology concerned with the study and diagnosis of human diseases involving hematolymphoid cells and tissues and blood coagulation.
Hematopathology is a unique field that encompasses both anatomic and clinical pathology while also using molecular technology and flow cytometric analysis. Along with flow cytometry, hematopathologists utilize various other tools and technologies—such as histology, immunohistochemistry, cytogenetics, DNA sequencing, and other molecular analysis—to make diagnoses and predict responses to therapy.
Hematopathologists specialize in looking at lymph nodes, bone marrow, and peripheral blood smears; they often sign out morphology as well as flow cytometry and are responsible for integrating the results of genetic studies. Diagnosis of hematolymphoid neoplasms requires extensive integration of morphologic, clinical, and ancillary testing data, all of which has an element of urgency that can keep things exciting.