1. Home
  2. Member Resources
  3. Pathology Case Challenge

Pathology Case Challenge

This program offers at least two challenging cases each month from the CAP Performance Improvement Program in Surgical Pathology. For each case, you will use a virtual microscope whole slide image of a surgical specimen to diagnose diseases.

You will be presented with information on each case including: specimen source, clinical history, laboratory findings, and a representative whole slide image of the surgical specimen. After you complete each case, you will receive a case summary with three multiple-choice questions that relate to the case.

Please note: DigitalScope® is supported with Microsoft Internet Explorer 11.0 (limited support for IE 9 and 10) or later, or FireFox 4.0 or later, or Safari 3 or the latest Google Chrome version.


A 27-year-old man presents with recent onset of abdominal pain. A computed tomography scan demonstrates an abdominal mass with multiple satellite nodules. A biopsy of the abdominal mass is performed, revealing a cellular undifferentiated tumor. Immunohistochemical studies reveal the tumor to be positive for cytokeratin AE1/AE3, focally positive for desmin in a paranuclear dot-like pattern, and positive for nuclear expression WT1 (using antibodies to the C-terminus).

Read the Pathology Case Challenge

Previous Case Challenges

View a list of previous cases using the virtual microscope to examine various surgical specimens and diagnose diseases.

MyCAP App - CAP Member App