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Previous Pathology Case Challenges

  • Breast

    A 62-year-old woman presents with a rapidly enlarging palpable breast mass. Mammography demonstrates a 5 cm irregular solid mass.

  • Heart

    A 60-year-old man presents with dyspnea on exertion and swollen legs. Physical examination shows pitting edema in both legs and ascites.

  • Stomach

    A 65-year-old man presents with vague abdominal pain. A CT scan reveals an abdominal mass near the greater curvature of the stomach.

  • Retroperitoneum

    A 47-year-old man presents with abdominal fullness, jaundice, and fatigue. Physical exam reveals multiple spider angiomata on the surface of his abdomen and large volume ascites.

  • Liver

    A 47-year-old man presents with abdominal fullness, jaundice, and fatigue. Physical exam reveals multiple spider angiomata on the surface of his abdomen and large volume ascites.

  • Ovary

    A 45-year-old nulliparous woman presents with a history of mild abdominal pain of 3 months’ duration. Ultrasound reveals a 10 cm right adnexal mass.

  • Kidney

    A 4-year-old girl is found to have an abdominal mass. Computed tomography scan confirms the presence of a solid and focally cystic left renal mass.

  • Abdomen

    A 45-year-old man presents with a history of abdominal discomfort. Radiologic studies reveal a relatively well-defined 12 cm mass abutting the left adrenal gland.

  • Breast

    A 67-year-old woman presents with a vague area of thickening in her left breast. Mammographic imaging is unremarkable, and ultrasound reveals an ill-defined mass which is excised.

  • Ovary

    A 51-year-old woman presents with abdominal discomfort and ascites. Imaging studies reveal bilateral ovarian masses.

  • Liver

    A 63-year-old woman presents with abdominal pain and swelling of several weeks’ duration. Radiologic imaging reveals an 11 cm heterogenous mass in the liver.

  • Spleen

    A 68-year-old man with a 3-week history of abdominal discomfort presents to the emergency department. Ultrasound reveals a massively enlarged spleen.

  • Peripancreatic Lymph Node

    A 58-year-old woman presents with diarrhea. Esophagogastroduodenoscopy reveals multiple ulcers throughout the upper gastrointestinal tract.

  • Thigh

    A 36-year-old man presents with an enlarging mass in his thigh. Physical exam demonstrates a large, firm, fusiform mass in the deep anterior thigh.

  • Breast

    A 55-year-old woman with a history of lung carcinoma presents with a 13 cm breast mass.

  • Uterine Cervix

    A 17-year-old girl presents with complaints of irregular vaginal bleeding. On clinical exam, she has a gelatinous multi-lobulated lesion protruding from the cervical os.

  • Retroperitoneum

    A 70-year-old woman presents with increasing abdominal girth, discomfort, and bilateral leg swelling over several months.

  • Left Flank

    A 47-year-old woman presents with a 12 cm left flank mass. Computed tomography scan shows a deep seated homogenous well-circumscribed mass.

  • Lung

    A 70-year-old woman with a long history of smoking presents with weight loss, cough, and shortness of breath of several months’ duration.

  • Liver

    A 70-year-old man presents with vague abdominal pain and increasing jaundice. His past medical history is notable for chronic hepatitis C.

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