Previous Pathology Case Challenges

A 45-year-old nulliparous woman presents with a history of mild abdominal pain of 3 months’ duration. Ultrasound reveals a 10 cm right adnexal mass.

A 4-year-old girl is found to have an abdominal mass. Computed tomography scan confirms the presence of a solid and focally cystic left renal mass.

A 45-year-old man presents with a history of abdominal discomfort. Radiologic studies reveal a relatively well-defined 12 cm mass abutting the left adrenal gland.

A 67-year-old woman presents with a vague area of thickening in her left breast. Mammographic imaging is unremarkable, and ultrasound reveals an ill-defined mass which is excised.

A 51-year-old woman presents with abdominal discomfort and ascites. Imaging studies reveal bilateral ovarian masses.

A 63-year-old woman presents with abdominal pain and swelling of several weeks’ duration. Radiologic imaging reveals an 11 cm heterogenous mass in the liver.

A 68-year-old man with a 3-week history of abdominal discomfort presents to the emergency department. Ultrasound reveals a massively enlarged spleen.

A 58-year-old woman presents with diarrhea. Esophagogastroduodenoscopy reveals multiple ulcers throughout the upper gastrointestinal tract.

A 36-year-old man presents with an enlarging mass in his thigh. Physical exam demonstrates a large, firm, fusiform mass in the deep anterior thigh.

A 55-year-old woman with a history of lung carcinoma presents with a 13 cm breast mass.

A 17-year-old girl presents with complaints of irregular vaginal bleeding. On clinical exam, she has a gelatinous multi-lobulated lesion protruding from the cervical os.

A 70-year-old woman presents with increasing abdominal girth, discomfort, and bilateral leg swelling over several months.

A 47-year-old woman presents with a 12 cm left flank mass. Computed tomography scan shows a deep seated homogenous well-circumscribed mass.

A 70-year-old woman with a long history of smoking presents with weight loss, cough, and shortness of breath of several months’ duration.

A 70-year-old man presents with vague abdominal pain and increasing jaundice. His past medical history is notable for chronic hepatitis C.

A 50-year-old man presents with longstanding hematuria and flank pain, and a right renal mass with retroperitoneal lymphadenopathy is identified on CT scan.

A 6-month-old baby boy presents to an outside hospital with cardiomyopathy of uncertain etiology. Cardiac transplantation is performed.

A 54-year-old man with long-standing diabetes mellitus, chronic renal failure, and no previous history of malignancy presented with shortness of breath. His chest x-ray revealed large bilateral pleural effusions but no lung masses or adjacent lymphadenopathy.

A 65-year-old right-handed woman with a long-standing history of headaches presents to the emergency room after having a witnessed seizure.

A 45-year-old woman presents to her internist with fatigue, constipation, dry skin, weight gain, and mild difficulty in swallowing over the past few months.