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Previous Pathology Case Challenges

  • Pancreas

    A 45-year-old woman presents to her internist with fatigue, constipation, dry skin, weight gain, and mild difficulty in swallowing over the past few months.

  • Thyroid

    A 45-year-old woman presents to her internist with fatigue, constipation, dry skin, weight gain, and mild difficulty in swallowing over the past few months.

  • Placenta

    A 28-year-old woman with prenatal history of oligohydramnios delivers an infant with polycystic kidney disease at 35 weeks’ gestation.

  • Spleen

    A 56-year-old man presents with a six-month history of unintentional weight loss, persistent fever, and night sweats. A complete blood count indicates anemia and thrombocytosis.

  • Heart

    A 50-year-old man presents to the ER with diffuse abdominal pain. His abdomen is markedly tender to palpation with significant guarding.

  • Small Intestine

    A 50-year-old man presents to the ER with diffuse abdominal pain. His abdomen is markedly tender to palpation with significant guarding.

  • Adrenal Gland

    A healthy, athletic 15-year-old girl is hit by a car while riding her bike, sustaining minor injuries. At the hospital, a CT scan demonstrates a left adrenal gland mass.

  • Spleen

    A 62-year-old man presents with sudden onset dizziness. In the emergency department, he appears lethargic and pale.

  • Adrenal Gland

    A 56-year-old woman presents with abdominal pain, bloating, and early satiety of several months’ duration.

  • Mediastinum

    A 60-year-old woman is involved in a motor vehicle accident and is admitted to the emergency department for evaluation of pleuritic chest pain complaints.

  • Soft Tissue of the Chest Wall

    A 55-year-old woman presents with non-productive cough of several- weeks duration. Computerized tomography shows a 9 x 9 cm mass of the left chest wall.

  • Adrenal Gland

    A 45-year-old woman presents to her internist with back pain for the past few months. A high level of DHEA-S in her serum is detected.

  • Pelvis

    A 35-year-old asymptomatic woman presents for a routine pelvic exam. Her gynecologist notes fullness within the pelvis and orders an MRI.

  • Posterior Mediastinal Mass

    A 9-month-old infant develops respiratory distress and is found to have a left posterior mediastinal mass and pleural effusion.

  • Liver

    A 63-year-old woman undergoes orthotopic liver transplantation. She has a history of liver disease first diagnosed 25 years ago.

  • Kidney

    A 67-year-old man presents with hematuria. An abdominal CT scan reveals a 9 cm mass in the upper pole of the left kidney.

  • Chest Wall

    A 72-year-old man presents with an enlarging chest wall mass. Gross examination of the resected specimen shows a well-circumscribed mass of multilobulated, yellow adipose tissue.

  • Colon

    A 65-year-old woman presents to the emergency department with watery diarrhea for five days. Her abdomen shows diffuse tenderness on palpation.

  • Liver

    An 82-year-old woman presents with vague abdominal pain and increasing jaundice. Her medical history is notable for primary sclerosing cholangitis.

  • Third Trimester Placenta

    A 27-year-old G1P0 woman is admitted in active labor at 37 weeks of gestation. Her second trimester routine ultrasound showed a 7.0 cm placental lesion.

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