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Previous Pathology Case Challenges

  • Adult Granulosa Cell Tumor

    A 55-year-old woman presents with several weeks of postmenopausal bleeding and abdominal pain. A pelvis CT scan demonstrates a 13 cm right adnexal mass.

  • Hematology

    A 62-year-old engineer presented with fatigue, pallor, and weight loss for the past two months. Clinical examination revealed a palpable spleen and skin pallor.

  • Vulva

    A 39-year-old woman with no significant past medical history presents with a single 4-cm nodule located on the labia majora.

  • Abdomen

    A 27-year-old man presents with recent onset of abdominal pain. CT scan demonstrates an abdominal mass with multiple satellite nodules.

  • Pancreas

    A 69-year-old woman presents to the ER with joint and back pain, nausea, weight loss, and diarrhea. CT scan reveals pancreatic and liver masses.

  • Ovary

    A 58-year-old woman with a prior history of pancreatic adenocarcinoma presents with abdominal pain and is found to have a 9 cm cystic left adnexal mass.

  • Lymph Node, Axilla

    A 61-year-old woman presents with an axillary mass. There are no other systemic symptoms or lymphadenopathy

  • Chest Wall

    A 52-year-old woman initially diagnosed and treated for breast cancer three years ago presents with a mass in the chest wall.

  • Ovary

    A 9-year-old girl presents to her pediatrician with premenarchal Tanner stage II-III breast development, mildly accelerated growth for chronological age, and vague abdominal

  • Presacral Mass

    A 57-year-old man presents with complaints of difficulty urinating and bone pain. Imaging reveals a 5 cm presacral mass and pelvic lymphadenopathy.

  • Parotid Gland

    A 70-year-old man presents with a rapidly growing right cheek mass with associated pain, facial nerve palsy, and cervical lymphadenopathy.

  • Colon

    A 44-year-old man presents with a slowly growing 10 cm firm polypoid mass of the right arm. On gross examination, the mass is tan-red and firm.

  • Arm Mass

    A 44-year-old man presents with a slowly growing 10 cm firm polypoid mass of the right arm. On gross examination, the mass is tan-red and firm.

  • Thigh

    A 40-year-old man presents with a large, painless mass of the left thigh. The mass is resected following diagnostic needle biopsies.

  • Retroperitoneum

    A 25-year-old man presents for follow up of a testicular mass, status post orchiectomy 8 months ago. A CT scan shows a large periaortic mass in the lower abdomen.

  • Testis

    A 37-year-old man presents with a right testicular mass. Testicular ultrasound reveals a 6 cm hypervascular mass.

  • Stomach

    A 60-year-old woman presents with fatigue and a 20-pound weight loss. Endoscopy reveals an 8 cm ulcerated mass located in the gastric antrum.

  • Ileum

    A 55-year-old man presents with a five-month history of abdominal pain and a 10-pound weight loss.

  • Colon

    A 43-year-old woman presents with complaints of longstanding, occasionally bloody diarrhea. Colonoscopy shows innumerable mucosal polyps.

  • Small Intestine

    A 21-year-old woman presents with intractable severe abdominal pain with nausea and vomiting. The patient’s history includes previous episodes of “upset stomach” and associated diarrhea.

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