Previous Pathology Case Challenges

A 22-year-old man with a history of colectomy presents with abdominal pain. Physical exam finds a palpable abdominal mass, which a CT scan confirms.

A 46-year-old woman presents with pelvic pain and abnormal vaginal bleeding. Endometrial biopsy shows proliferative endometrium.

A 45-year-old man presents with bilateral gynecomastia. On physical examination, a left testicular mass is identified.

A 62-year-old man presents with a painless testicular mass. A radical orchiectomy is performed, revealing a solid lobular tan mass measuring 4 cm.

A 67-year-old man presents with diarrhea, nausea, and intermittent fever. His medical history includes a thyroid carcinoma and a melanoma on his upper back, widely excised.

A 32-year-old woman undergoing antenatal care has an abdominal wall nodule measuring 2 cm early mid-trimester, which increases to 5 cm in the third trimester.

A 47-year-old woman with a history of sickle cell disease presents with increasing abdominal pain. A CBC demonstrates anemia and a CT scan reveals bilateral adrenal masses.

A 19-year-old otherwise healthy man presents with a history of intermittent pain associated with an enlarging left neck mass.

A 3-year-old boy presents with a 12 cm solid heterogeneous mass within his right kidney.

A 62-year-old man presents with hematuria and flank pain. A computed tomography scan shows a 6 cm mass in the right kidney.

A 60-year-old woman presents​ ​with shortness of breath and recent onset of weight loss. She expires shortly after admission.

A 6-year-old girl with a history of persistent asthma is brought to urgent care with 5 days of cough and cold symptoms. She is in cardiopulmonary arrest.

A 53-year-old woman presents with abdominal pain and is found to have an ovarian mass.

A 55-year-old woman presents with several weeks of postmenopausal bleeding and abdominal pain. A pelvis CT scan demonstrates a 13 cm right adnexal mass.

A 47-year-old man presents with abdominal fullness, jaundice, and fatigue. Physical exam reveals multiple spider angiomata on the surface of his abdomen and large volume ascites.

A 47-year-old man presents with abdominal fullness, jaundice, and fatigue. Physical exam reveals multiple spider angiomata on the surface of his abdomen and large volume ascites.

A 45-year-old nulliparous woman presents with a history of mild abdominal pain of 3 months’ duration. Ultrasound reveals a 10 cm right adnexal mass.

A 4-year-old girl is found to have an abdominal mass. Computed tomography scan confirms the presence of a solid and focally cystic left renal mass.

A 45-year-old man presents with a history of abdominal discomfort. Radiologic studies reveal a relatively well-defined 12 cm mass abutting the left adrenal gland.

A 67-year-old woman presents with a vague area of thickening in her left breast. Mammographic imaging is unremarkable, and ultrasound reveals an ill-defined mass which is excised.