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- 2026 Pathology Quality Measures
The Pathologists Quality Registry offers 13 quality measures. Seven are Merit-based Incentive Payment System (MIPS) clinical quality measures (CQMs). The remaining six are pathology measures developed by the CAP and approved by the CMS as qualified clinical data registry (QCDR) measures—exclusively available in the Pathologists Quality Registry. To better understand how to review and interpret measure specifications, the CMS has developed Quality Payment Program Measure Specification and Measure Flow Guide for MIPS Clinical Quality Measures.
Important 2026 Updates
CAP 22: Biopsy Reporting Time to Clinician is no longer available in the program.
CAP 38: Prostate Cancer Reporting: Complete Analysis is no longer available in the program
CAP 41: Basal Cell Skin Cancer: Complete Reporting is no longer available in the program
Pathology Specific QPP Measures
These measures can be reported to the CMS using the Pathologists Quality Registry, through billing/claims, and other registries.
| QPP 249: Barrett Esophagus Pathology Reporting Registry and Claims Specifications |
| QPP 250: Radical Prostatectomy Pathology Reporting Registry and Claims Specifications |
| QPP 395: Lung Cancer Reporting (biopsy/cytology specimens) Registry and Claims Specifications |
| QPP 396: Lung Cancer Reporting (resection specimens) Registry and Claims Specifications |
| QPP 397: Melanoma Reporting Registry and Claims Specifications |
These measures can be reported to the CMS using the Pathologists Quality Registry and other registries.
| QPP 440: Skin Cancer: Biopsy Reporting Time - Pathologist to Clinician Registry Specifications (American Academy of Dermatology measure) |
| QPP 491: Mismatch Repair (MMR) or Microsatellite Instability (MSI) Biomarker Testing Status in Colorectal Carcinoma, Endometrial, Gastroesophageal, or Small Bowel Carcinoma Registry Specifications |
Scores for the QPP measures depend on the benchmarks CMS sets for each measure. Estimate your score by viewing the QPP Measure Benchmarks.
Pathologists Quality Registry QCDR Measures
These measures can be reported to the CMS only with the Pathologists Quality Registry.
For 2025, three QCDR measures have historical benchmarks. Estimate your score by viewing the QCDR Measure Benchmarks.
2025 Pathology Quality Measures Frequently Asked Questions
The CMS recommends that eligible professionals check with the QPP HelpDesk for more information on measures and the QPP.
Professionals may contact the QPP Help Desk.
7:00 AM–7:00 PM CT Monday - Friday
Email: QPP@cms.hhs.gov
Phone: 866-288-8292
Suggest New Quality Measures
The CAP wants to know what matters to pathologists for quality measures. Submit your ideas for measure concepts today! Access the measure concept intake form or contact measures@cap.org for more information about nominating a concept.
Claims-Based Reporting Information
The CAP developed an instruction sheet on claims-based reporting to assist with submitting data on quality measures for MIPS through claims. The corresponding document provides the CPT II and quality data codes (QDC) and descriptors for the 2026 QPP measures.
Access 2024 Pathology Quality Measures Information