• Closing the Gap: How the CAP Is Advancing Accuracy in Lab Testing Through Harmonization and Standardization

    The article highlights the critical role of laboratory testing in diagnosing and managing diseases, emphasizing the importance of accuracy in lab results. It explores how the College of American Pathologists (CAP) is addressing variability in test outcomes through harmonization and standardization efforts. By leveraging its Accuracy-Based Programs and proficiency testing materials, CAP enables labs and manufacturers to align their results with certified reference methods, improving diagnostic reliability for conditions like kidney disease, diabetes, and heart disease.

  • How to Not Freeze on a Frozen

    Practical guidance for new-in-practice pathologists focusing on the challenges of frozen section analysis. This article outlines key strategies to manage stress and improve diagnostic accuracy under time pressure, including understanding patient history, recognizing procedural limitations, troubleshooting technical issues, and seeking support from colleagues. The piece emphasizes thoughtful decision-making and patient-centered care to help new-in-practice pathologists navigate this high-stakes responsibility with confidence.

  • DEIA Committee Member Spotlight: Angela Lapus, MD, MPH, FCAP

    Learn about Diversity, Equity, Inclusion, & Accessibility Committee member Angela Lapus, MD, MPH, FCAP.

  • Tissue Provenance: Personalized Health Care Starts with Analyzing the Correct Person

    Tissue provenance is the concept of assuring that tissue, whether in a container, on a slide or a swab, or in an instrument, is from the original source and authentic.

  • Leading Quality Improvement as a New-in-Practice Pathologist: 10 Tips for Making an Impact

    Find 10 practical tips for early-career pathologists to lead quality improvement (QI) initiatives in healthcare settings. this article by Jennifer Woo, MD, FCAP highlights how QI can enhance diagnostic accuracy, streamline lab workflows, and foster interdepartmental collaboration even without formal leadership roles.

  • Improvements on the Liquid Biopsy: Exosomes

    Explore how exosomes are advancing liquid biopsy technology, offering new possibilities for cancer diagnostics, monitoring, and personalized treatment strategies.

  • Immunohistochemical Surrogates of Molecular Genetic Alterations in Soft Tissue Tumors

    Immunohistochemical (IHC) markers can serve as surrogates for molecular genetic events, providing a practical tool for early and accurate diagnosis. These markers are particularly useful in soft tissue tumor pathology, where both benign and malignant neoplasms often have defining genetic events that result in protein overexpression or loss.

  • Clonal Hematopoiesis and Inflammation

    Explore the intricate relationship between Clonal Hematopoiesis of Indeterminate Potential (CHIP), inflammation, and cardiovascular disease. Learn about the genetic mutations involved, factors affecting CHIP, and potential therapeutic strategies to mitigate associated risks.

  • Allogeneic Cellular Therapy – Diagnostic Challenges and Opportunities for Laboratory Practice

    While allogenic cellular therapies (ACTs) offer promising off-the-shelf treatment options, addressing challenges in their development and implementation is essential for improving their safety, efficacy, and accessibility to a broader patient population.

  • CAP Updates Guideline to Improve HPV Testing in Head and Neck Cancers

    The guideline, "Human Papillomavirus (HPV) Testing in Head and Neck Carcinomas," published in Archives of Pathology & Laboratory Medicine, reflects the latest research and technological advancements to improve diagnostic accuracy and patient outcomes.

  • Learn in the Morning, Recharge in the Afternoon

    By integrating personal and professional endeavors, you can have your cake and eat it too.  Pathology on the Coast is a rare opportunity to learn about current pathology topics in the morning and enjoy leisure and relaxation in the afternoon. 

  • Molecular Biomarkers in Salivary Gland Neoplasms

    Genetic and molecular testing are revolutionizing the diagnosis and treatment of salivary gland neoplasms, aiding in tumor classification, prognostication, and targeted therapy selection. This article explores key diagnostic biomarkers, emerging therapeutic targets, and the challenges of molecular testing, highlighting its growing role in precision oncology for these rare and heterogeneous tumors.

  • DNA Methylation to the Rescue: An Update for Pathologists Navigating the Future of Precision Tumor Diagnostics

    While once a distant possibility, the advancement of DNA methylation techniques is now bringing the potential for a pan-cancer DNA methylation classifiers closer to realization. 

  • Pathologists at the Forefront: Shaping the Future of Cancer Treatment with Molecular Tumor Boards

  • Navigating the Visa Process as a Pathology Resident

    Navigating the job market and visa processes can be challenging; learn about the visa options available for pathology residents and the requirements and benefits of each.

  • Post-COVID-19 Blood Supply Challenges: Requests for Blood from Unvaccinated Donors

  • Pathologists' Reflections on Filipino Heritage: Determination, Adaptability, Resilience

    Dr. Victor Cabañas and Dr. Anthony Victorio discuss how their Filipino upbringing and culture influenced their experiences and careers in pathology.

  • Clinical Informatics Education for Pathology Residents

    Pathologists who specialize in clinical informatics (also known as pathology informaticists or pathology informaticians) serve as medical directors for laboratory information systems and/or the laboratory components of electronic health records (EHRs). Are you interested in pursuing clinical informatics? Learn more.

  • Top 5 Takeaways on FDA LDT Risk Classification

    Review the five key takeaways from the CAP's recent webinar on the differences between FDA and CLIA risk classifications of laboratory-developed tests.

  • College of American Pathologists Challenges FDA LDT Regulation with Amicus Brief Filing

    The College of American Pathologists (CAP) filed an amicus brief on against the Food and Drug Administration (FDA) and its regulation of laboratory-developed tests (LDTs), challenging the LDT rulemaking by the FDA, which acted arbitrarily and capriciously in violation of the Administrative Procedure Act.

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